Abstract
Persistent hypocalcaemic tetany in a breast-fed neonate made us suspect DiGeorge's syndrome, particularly as the baby had an abnormal facies, and a ventricular septal defect. Immuno-reconstitution was successfully achieved by thymic transplant. Evidence of immuno-reconstitution on the basis of the histology of the post-transplant thymus has not been previously recorded.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- August C. S., Rosen F. S., Filler R. M., Janeway C. A., Markowski B., Kay H. E. Implantation of a foetal thymus, restoring immunological competence in a patient with thymic aplasia (Digeorge's syndrome). Lancet. 1968 Dec 7;2(7580):1210–1211. doi: 10.1016/s0140-6736(68)91693-0. [DOI] [PubMed] [Google Scholar]
- Cleveland W. W., Fogel B. J., Brown W. T., Kay H. E. Foetal thymic transplant in a case of Digeorge's syndrome. Lancet. 1968 Dec 7;2(7580):1211–1214. doi: 10.1016/s0140-6736(68)91694-2. [DOI] [PubMed] [Google Scholar]
- Huber J., Cholnoky P., Zoethout H. E. Congenital aplasia of parathyroid glands and thymus. Arch Dis Child. 1967 Apr;42(222):190–192. doi: 10.1136/adc.42.222.190. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kretschmer R., Say B., Brown D., Rosen F. S. Congenital aplasia of the thymus gland (DiGeorge's syndrome). N Engl J Med. 1968 Dec 12;279(24):1295–1301. doi: 10.1056/NEJM196812122792401. [DOI] [PubMed] [Google Scholar]
- Pabst H. F., Wright W. C., LeRiche J., Stiehm E. R. Partial DiGeorge syndrome with substantial cell-mediated immunity. Am J Dis Child. 1976 Mar;130(3):316–319. doi: 10.1001/archpedi.1976.02120040094018. [DOI] [PubMed] [Google Scholar]
- Taitz L. S., Zarate-Salvador C., Schwartz E. Congenital absence of the parathyroid and thymus glands in an infant. (3 and 4 pharyngeal pouch syndrome). Pediatrics. 1966 Sep;38(3):412–418. [PubMed] [Google Scholar]