Abstract
Plasma 25-hydroxy cholecalciferol (25-OH vitamin D) concentrations were measured in 31 adult Saudi Arabian women who presented with acute minor illness. Patients with chronic diseases, malignancy and overt metabolic bone disease were excluded from this study. The median plasma 25-OH vitamin D concentration was 6 ng/ml (range: 2-18 ng/ml). Only three subjects had a concentration within the normal range (10-55 ng/ml). Plasma 25-OH vitamin D concentrations were significantly lower in subjects living in apartments than in those living in villas or rural areas (P less than 0.02). When direct questioning was used to assess exposure to sunlight, plasma 25-OH vitamin D concentrations were significantly lower in those subjects whose average exposure was less than 30 min daily than those whose exposure was more than 30 min daily (P = 0.002). Our findings confirm the importance of inadequate exposure to sunlight in the aetiology of vitamin D deficiency. Social customs may contribute to this deficiency in spite of abundant sunshine. Direct questioning to assess the adequacy of sunlight exposure is an essential part of history taking in cases of suspected vitamin D deficiency.
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Selected References
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- Clemens T. L., Adams J. S., Henderson S. L., Holick M. F. Increased skin pigment reduces the capacity of skin to synthesise vitamin D3. Lancet. 1982 Jan 9;1(8263):74–76. doi: 10.1016/s0140-6736(82)90214-8. [DOI] [PubMed] [Google Scholar]
- Gupta M. M., Round J. M., Stamp T. C. Spontaneous cure of vitamin-D deficiency in Asians during summer in Britain. Lancet. 1974 Apr 6;1(7858):586–588. doi: 10.1016/s0140-6736(74)92648-8. [DOI] [PubMed] [Google Scholar]
- Hodkinson H. M., Round P., Stanton B. R., Morgan C. Sunlight, vitamin D, and osteomalacia in the elderly. Lancet. 1973 Apr 28;1(7809):910–912. doi: 10.1016/s0140-6736(73)91362-7. [DOI] [PubMed] [Google Scholar]
- Preece M. A., McIntosh W. B., Tomlinson S., Ford J. A., Dunnigan M. G., O'Riordan J. L. Vitamin-D deficiency among Asian immigrants to Britain. Lancet. 1973 Apr 28;1(7809):907–910. doi: 10.1016/s0140-6736(73)91361-5. [DOI] [PubMed] [Google Scholar]
- Serenius F., Elidrissy A. T., Dandona P. Vitamin D nutrition in pregnant women at term and in newly born babies in Saudi Arabia. J Clin Pathol. 1984 Apr;37(4):444–447. doi: 10.1136/jcp.37.4.444. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stanbury S. W. Vitamin D and hyperparathyroidism: the Lumleian Lecture 1981. J R Coll Physicians Lond. 1981 Oct;15(4):205-9, 212-7. [PMC free article] [PubMed] [Google Scholar]