Abstract
Acute renal failure may occur in the nephrotic syndrome due to minor glomerular changes, especially in the elderly. We describe five cases and review the literature. Previous renal damage due to ischaemia and drugs may be important in pathogenesis. We stress the importance of active management of these cases, as the renal lesions are reversible and recovery can be expected.
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Selected References
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- Bohman S. O., Jaremko G., Bohlin A. B., Berg U. Foot process fusion and glomerular filtration rate in minimal change nephrotic syndrome. Kidney Int. 1984 Apr;25(4):696–700. doi: 10.1038/ki.1984.76. [DOI] [PubMed] [Google Scholar]
- Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 28-1978. N Engl J Med. 1978 Jul 20;299(3):136–145. doi: 10.1056/NEJM197807202990309. [DOI] [PubMed] [Google Scholar]
- Chamberlain M. J., Pringle A., Wrong O. M. Oliguric renal failure in the nephrotic syndrome. Q J Med. 1966 Apr;35(138):215–235. [PubMed] [Google Scholar]
- Conolly M. E., Wrong O. M., Jones N. F. Reversible renal failure in idiopathic nephrotic syndrome with minimal glomerular changes. Lancet. 1968 Mar 30;1(7544):665–668. doi: 10.1016/s0140-6736(68)92101-6. [DOI] [PubMed] [Google Scholar]
- Coward R. A., Delamore I. W., Mallick N. P., Robinson E. L. The importance of urinary immunoglobulin light chain isoelectric point (pI) in nephrotoxicity in multiple myeloma. Clin Sci (Lond) 1984 Feb;66(2):229–232. doi: 10.1042/cs0660229. [DOI] [PubMed] [Google Scholar]
- Esparza A. R., Kahn S. I., Garella S., Abuelo J. G. Spectrum of acute renal failure in nephrotic syndrome with minimal (or minor) glomerular lesions. Role of hemodynamic factors. Lab Invest. 1981 Dec;45(6):510–521. [PubMed] [Google Scholar]
- Hulter H. N., Bonner E. L., Jr Lipoid nephrosis appearing as acute oliguric renal failure. Arch Intern Med. 1980 Mar;140(3):403–405. [PubMed] [Google Scholar]
- Kopple J. D., Coburn J. W. Evaluation of chronic uremia. Importance of serum urea nitrogen, serum creatinine, and their ratio. JAMA. 1974 Jan 7;227(1):41–44. doi: 10.1001/jama.227.1.41. [DOI] [PubMed] [Google Scholar]
- Llach F., Koffler A., Finck E., Massry S. G. On the incidence of renal vein thrombosis in the nephrotic syndrome. Arch Intern Med. 1977 Mar;137(3):333–336. [PubMed] [Google Scholar]
- Lyons H., Pinn V. W., Cortell S., Cohen J. J., Harrington J. T. Allergic interstitial nephritis causing reversible renal failure in four patients with idiopathic nephrotic syndrome. N Engl J Med. 1973 Jan 18;288(3):124–128. doi: 10.1056/NEJM197301182880304. [DOI] [PubMed] [Google Scholar]
- Navar L. G., Rosivall L. Contribution of the renin-angiotensin system to the control of intrarenal hemodynamics. Kidney Int. 1984 Jun;25(6):857–868. doi: 10.1038/ki.1984.102. [DOI] [PubMed] [Google Scholar]
- Raij L., Keane W. F., Leonard A., Shapiro F. L. Irreversible acute renal failure in idiopathic nephrotic syndrome. Am J Med. 1976 Aug;61(2):207–214. doi: 10.1016/0002-9343(76)90171-6. [DOI] [PubMed] [Google Scholar]
- Smolens P., Venkatachalam M., Stein J. H. Myeloma kidney cast nephropathy in a rat model of multiple myeloma. Kidney Int. 1983 Aug;24(2):192–204. doi: 10.1038/ki.1983.144. [DOI] [PubMed] [Google Scholar]
- Stewart R. B., Hale W. E., Marks R. G. Effects of nonsteroidal anti-inflammatory drugs on renal function in the elderly. South Med J. 1982 Jul;75(7):824–826. doi: 10.1097/00007611-198207000-00015. [DOI] [PubMed] [Google Scholar]
- Trollfors B., Norrby R. Estimation of glomerular filtration rate by serum creatinine and serum beta 2-microglobulin. Nephron. 1981;28(4):196–199. doi: 10.1159/000182197. [DOI] [PubMed] [Google Scholar]