Abstract
The fertility of 70 men with Crohn's disease and a group of age matched controls were compared. Crohn's disease was associated with a significant reduction in family size independent of steroid or sulphasalazine treatment.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Birnie G. G., McLeod T. I., Watkinson G. Incidence of sulphasalazine-induced male infertility. Gut. 1981 Jun;22(6):452–455. doi: 10.1136/gut.22.6.452. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Freeman J. G., Reece V. A., Venables C. W. Sulphasalazine and spermatogenesis. Digestion. 1982;23(1):68–71. doi: 10.1159/000198712. [DOI] [PubMed] [Google Scholar]
- O'Moráin C., Smethurst P., Doré C. J., Levi A. J. Reversible male infertility due to sulphasalazine: studies in man and rat. Gut. 1984 Oct;25(10):1078–1084. doi: 10.1136/gut.25.10.1078. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Summers R. W., Switz D. M., Sessions J. T., Jr, Becktel J. M., Best W. R., Kern F., Jr, Singleton J. W. National Cooperative Crohn's Disease Study: results of drug treatment. Gastroenterology. 1979 Oct;77(4 Pt 2):847–869. [PubMed] [Google Scholar]
- Toovey S., Hudson E., Hendry W. F., Levi A. J. Sulphasalazine and male infertility: reversibility and possible mechanism. Gut. 1981 Jun;22(6):445–451. doi: 10.1136/gut.22.6.445. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Toth A. Reversible toxic effect of salicylazosulfapyridine on semen quality. Fertil Steril. 1979 May;31(5):538–540. doi: 10.1016/s0015-0282(16)44000-8. [DOI] [PubMed] [Google Scholar]