Skip to main content
NCBI home page
Applied and Environmental Microbiology logoLink to Applied and Environmental Microbiology
. 1982 Mar;43(3):619–622. doi: 10.1128/aem.43.3.619-622.1982

Biodegradation of [14C]Tri-p-Cresyl Phosphate in a Laboratory Activated-Sludge System

Yuoh Ku 1, George H Alvarez 1
PMCID: PMC241884  PMID: 16345968

Abstract

Biodegradation of [14C]tri-p-cresyl phosphate was studied in a laboratory model sewage treatment system to develop information on the nature of its transformation products. In 24-h experiments, 70 to 80% of tri-p-cresyl phosphate added at the 1-μg/ml level was degraded. The remaining parent compound was associated with the sludge solids. The major metabolite extracted with ethyl ether from the aqueous phase was identified as p-hydroxybenzoic acid by gas chromatography-mass spectrometry. Two unstable ether-extractable metabolites were not identified. The half-life of [14C]tri-p-cresyl phosphate was estimated to be 7.5 h.

Full text

PDF
619

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BONDY H. F., FIELD E. J., WORDEN A. N., HUGHES J. P. A study on the acute toxicity of the tri-aryl phosphates used as plasticizers. Br J Ind Med. 1960 Jul;17:190–200. doi: 10.1136/oem.17.3.190. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. DAGLEY S., PATEL M. D. Oxidation of p-cresol and related compounds by a Pseudomonas. Biochem J. 1957 Jun;66(2):227–233. doi: 10.1042/bj0660227. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Dollahite J. W., Pierce K. R. Neurologic disturbances due to triaryl phosphate toxicity. Am J Vet Res. 1969 Aug;30(8):1461–1464. [PubMed] [Google Scholar]
  4. Howard P. H., Deo P. G. Degradation of aryl phosphates in aquatic environments. Bull Environ Contam Toxicol. 1979 Jun;22(3):337–344. doi: 10.1007/BF02026952. [DOI] [PubMed] [Google Scholar]
  5. Kirsch E. J., Etzel J. E. Microbial decomposition of pentachlorophenol. J Water Pollut Control Fed. 1973 Feb;45(2):359–364. [PubMed] [Google Scholar]
  6. Pickard M. A., Whelihan J. A., Westlake D. W. Utilization of triaryl phosphates by a mixed bacterial population. Can J Microbiol. 1975 Feb;21(2):140–145. doi: 10.1139/m75-021. [DOI] [PubMed] [Google Scholar]
  7. SMITH H. V., SPALDING J. M. Outbreak of paralysis in Morocco due to ortho-cresyl phosphate poisoning. Lancet. 1959 Dec 5;2(7110):1019–1021. doi: 10.1016/s0140-6736(59)91486-2. [DOI] [PubMed] [Google Scholar]
  8. SUSSER M., STEIN Z. An outbreak of tri-ortho-cresyl phosphate (T.O.C.P.) poisoning in Durban. Br J Ind Med. 1957 Apr;14(2):111–120. doi: 10.1136/oem.14.2.111. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Applied and Environmental Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES