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. 1982 Oct;44(4):871–877. doi: 10.1128/aem.44.4.871-877.1982

Bacterial Nitration of 4-Chlorobiphenyl

Michel Sylvestre 1, Robert Massé 1, François Messier 1, Johanne Fauteux 1, Jean-Guy Bisaillon 1, Réjean Beaudet 1
PMCID: PMC242111  PMID: 16346111

Abstract

In the course of a study dealing with the biodegradation of 4-chlorobiphenyl by strain B-206, we noticed that the gram-negative bacterium accumulated different metabolic intermediates depending on the nitrogen source of the medium. Hence, in the presence of nitrate, strain B-206 produced four compounds which were identified as 2- and 4-hydroxy-4′-chlorobiphenyl and 2- and 4-hydroxy-mononitro-4′-chlorobiphenyl. The accumulation of these compounds in the culture medium indicated the presence of a monooxygenase in strain B-206 leading to the production of arene oxide intermediates. The possible transformation of 4-chlorobiphenyl to an arene oxide by this bacterial strain is a matter of concern because of the high reactivity of these arene oxides with biological material.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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