Abstract
The fermentation ability of a strain of Kluyveromyces fragilis, already selected for rapid lactose-fermenting capability, was improved dramatically by the addition of unsaturated fatty acids and ergosterol to the medium. The fermentation time of a 20% whey-lactose medium was decreased from over 90 h to less than 60 h. The lipids were shown to be taken up by the organism, and the effects on specific growth rate and biomass production were determined.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bloch K., Vance D. Control mechanisms in the synthesis of saturated fatty acids. Annu Rev Biochem. 1977;46:263–298. doi: 10.1146/annurev.bi.46.070177.001403. [DOI] [PubMed] [Google Scholar]
- HUNGATE R. E. The anaerobic mesophilic cellulolytic bacteria. Bacteriol Rev. 1950 Mar;14(1):1–49. doi: 10.1128/br.14.1.1-49.1950. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ingram L. O. Regulation of fatty acid composition in Escherichia coli: a proposed common mechanism for changes induced by ethanol, chaotropic agents, and a reduction of growth temperature. J Bacteriol. 1982 Jan;149(1):166–172. doi: 10.1128/jb.149.1.166-172.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jollow D., Kellerman G. M., Linnane A. W. The biogenesis of mitochondria. 3. The lipid composition of aerobically and anaerobically grown Saccharomyces cerevisiae as related to the membrane systems of the cells. J Cell Biol. 1968 May;37(2):221–230. doi: 10.1083/jcb.37.2.221. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Resnick M. A., Mortimer R. K. Unsaturated fatty acid mutants of Saccharomyces cerevisiae. J Bacteriol. 1966 Sep;92(3):597–600. doi: 10.1128/jb.92.3.597-600.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
- TCHEN T. T., BLOCH K. On the mechanism of enzymatic cyclization of squalene. J Biol Chem. 1957 Jun;226(2):931–939. [PubMed] [Google Scholar]
- Taylor F. R., Parks L. W. Metabolic interconversion of free sterols and steryl esters in Saccharomyces cerevisiae. J Bacteriol. 1978 Nov;136(2):531–537. doi: 10.1128/jb.136.2.531-537.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Thomas D. S., Hossack J. A., Rose A. H. Plasma-membrane lipid composition and ethanol tolerance in Saccharomyces cerevisiae. Arch Microbiol. 1978 Jun 26;117(3):239–245. doi: 10.1007/BF00738541. [DOI] [PubMed] [Google Scholar]
- Thomas D. S., Rose A. H. Inhibitory effect of ethanol on growth and solute accumulation by Saccharomyces cerevisiae as affected by plasma-membrane lipid composition. Arch Microbiol. 1979 Jul;122(1):49–55. doi: 10.1007/BF00408045. [DOI] [PubMed] [Google Scholar]