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Intraperitoneal injection of Tat peptides had no effect on locomotor function of unanesthetized mice
| Agents | Placing | Grasping |
|---|---|---|
| Vehicle | 6 (0) | 6 (0) |
| PSD-95 PDZ2, 8 mg/kg | 6 (0) | 6 (0) |
| Tat- PSD-95 PDZ2, 8 mg/kg | 6 (0) | 6 (0) |
| Mutated Tat- PSD-95 PDZ2, 8 mg/kg | 6 (0) | 6 (0) |
Note: Data were expressed as mean (S.E.M). Six trials are taken for each testing. Score 1 for each normal response and score 0 when the animals fail. PDZ: PSD-95, Dlg, and ZO-1; PSD-95: postsynaptic density protein-95.
