Skip to main content
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 1981 Mar;57(665):156–158. doi: 10.1136/pgmj.57.665.156

Lysozyme and hypokalaemia

M A Mir, S C Lodha
PMCID: PMC2424880  PMID: 6949142

Abstract

Serum potassium, lysozyme and urinary lysozyme measurements were made in 98 patients with tuberculosis, 18 with sarcoidosis and 30 with acute myeloid leukaemia. Serum K concentration fell below 3·5 mmol/l in 17 of the 30 leukaemic patients and only 7 of these had raised serum lysozyme concentrations. None of the patients in the tuberculosis-sarcoidosis group with lysozymaemia or lysozymuria developed hypokalaemia. This study suggests that raised lysozyme concentrations are not causally related to hypokalaemia.

Full text

PDF
156

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BUTLER E. A., FLYNN F. V. The occurrence of post-gamma protein in urine: a new protein abnormality. J Clin Pathol. 1961 Mar;14:172–178. doi: 10.1136/jcp.14.2.172. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Klastersky J., Vanderklen B., Daneau D., Mathiew M. Carbenicillin and hypokalemia. Ann Intern Med. 1973 May;78(5):774–775. doi: 10.7326/0003-4819-78-5-774. [DOI] [PubMed] [Google Scholar]
  3. Lodha S. C., Mir M. A. Usefulness of serum lysozyme measurement in diagnosis of intrathoracic lymphadenopathy. Tubercle. 1980 Jun;61(2):81–85. doi: 10.1016/0041-3879(80)90014-8. [DOI] [PubMed] [Google Scholar]
  4. Mir M. A., Brabin B., Tang O. T., Leyland M. J., Delamore I. W. Hypokalaemia in acute myeloid leukaemia. Ann Intern Med. 1975 Jan;82(1):54–57. doi: 10.7326/0003-4819-82-1-54. [DOI] [PubMed] [Google Scholar]
  5. Mir M. A., Delamore I. W. Hypouricaemia and proximal renal tubular dysfunction in acute myeloid leukaemia. Br Med J. 1974 Sep 28;3(5934):775–777. doi: 10.1136/bmj.3.5934.775. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Mir M. A., Delamore I. W. Metabolic disorders in acute myeloid leukaemia. Br J Haematol. 1978 Sep;40(1):79–92. doi: 10.1111/j.1365-2141.1978.tb03641.x. [DOI] [PubMed] [Google Scholar]
  7. Muggia F. M., Heinemann H. O., Farhangi M., Osserman E. F. Lysozymuria and renal tubular dysfunction in monocytic and myelomonocytic leukemia. Am J Med. 1969 Sep;47(3):351–366. doi: 10.1016/0002-9343(69)90219-8. [DOI] [PubMed] [Google Scholar]
  8. Osserman E. F., Lawlor D. P. Serum and urinary lysozyme (muramidase) in monocytic and monomyelocytic leukemia. J Exp Med. 1966 Nov 1;124(5):921–952. doi: 10.1084/jem.124.5.921. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. PARRY R. M., Jr, CHANDAN R. C., SHAHANI K. M. A RAPID AND SENSITIVE ASSAY OF MURAMIDASE. Proc Soc Exp Biol Med. 1965 Jun;119:384–386. doi: 10.3181/00379727-119-30188. [DOI] [PubMed] [Google Scholar]
  10. PROCKOP D. J., DAVIDSON W. D. A STUDY OF URINARY AND SERUM LYSOZYME IN PATIENTS WITH RENAL DISEASE. N Engl J Med. 1964 Feb 6;270:269–274. doi: 10.1056/NEJM196402062700602. [DOI] [PubMed] [Google Scholar]
  11. Pascual R. S., Gee J. B., Finch S. C. Usefulness of serum lysozyme measurement in diagnosis and evaluation of sarcoidosis. N Engl J Med. 1973 Nov 15;289(20):1074–1076. doi: 10.1056/NEJM197311152892007. [DOI] [PubMed] [Google Scholar]
  12. Perillie P. E., Khan K., Finch S. C. Serum lysozyme in pulmonary tuberculosis. Am J Med Sci. 1973 Apr;265(4):297–302. doi: 10.1097/00000441-197304000-00005. [DOI] [PubMed] [Google Scholar]
  13. Pickering T. G., Catovsky D. Hypokalaemia and raised lysozyme levels in acute myeloid leukaemia. Q J Med. 1973 Oct;42(168):677–682. [PubMed] [Google Scholar]
  14. Pruzanski W., Platts M. E. Serum and urinary proteins, lysozyme (muramidase), and renal dysfunction in mono- and myelomonocytic leukemia. J Clin Invest. 1970 Sep;49(9):1694–1708. doi: 10.1172/JCI106387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Rodriguez V., Green S., Bodey G. P. Serum electrolyte abnormalities associated with the administration of polymyxin B in febrile leukemic patients. Clin Pharmacol Ther. 1970 Jan-Feb;11(1):106–111. doi: 10.1002/cpt1970111106. [DOI] [PubMed] [Google Scholar]
  16. Rosenthal D. S., Maglio R., Moloney W. C. Muramidasuria and hyperkaluria in the chloroleukemic rat. Proc Soc Exp Biol Med. 1972 Nov;141(2):499–500. doi: 10.3181/00379727-141-36807. [DOI] [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES