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. 1981 May;57(667):317–320. doi: 10.1136/pgmj.57.667.317

Congenital adrenal hyperplasia in a 66-year-old female.

A D Wright, T C Harvey, G Holder, D C Anderson, B T Rudd
PMCID: PMC2424924  PMID: 7301674

Abstract

A 66-year-old genotypically female patient was reared as a man. Investigations showed a partial adrenal 21-hydroxylase deficiency, and pituitary gonadotrophin secretion typical of a post-menopausal woman.

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Selected References

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  1. Anderson D. C., Hopper B. R., Lasley B. L., Yen S. S. A simple method for the assay of eight steroids in small volumes of plasma. Steroids. 1976 Aug;28(2):179–196. doi: 10.1016/0039-128x(76)90108-2. [DOI] [PubMed] [Google Scholar]
  2. BONGIOVANNI A. M., ROOT A. W. The adrenogenital syndrome. N Engl J Med. 1963 Jun 6;268:1283–contd. doi: 10.1056/NEJM196306062682308. [DOI] [PubMed] [Google Scholar]
  3. Bacon G. E., Spencer M. L., Kelch R. P. Effect of cortisol treatment on hormonal relationships in congenital adrenal hyperplasia. Clin Endocrinol (Oxf) 1977 Feb;6(2):113–126. doi: 10.1111/j.1365-2265.1977.tb02002.x. [DOI] [PubMed] [Google Scholar]
  4. Fukushima D. K., Finkelstein J. W., Yoshida K., Boyar R. M., Hellman L. Pituitary-adrenal activity in untreated congenital adrenal hyperplasia. J Clin Endocrinol Metab. 1975 Jan;40(1):1–12. doi: 10.1210/jcem-40-1-1. [DOI] [PubMed] [Google Scholar]
  5. Galal O. M., Rudd B. T., Drayer N. M. Evaluation of deficiency of 21-hydroxylation in patients with congenital adrenal hyperplasia. Arch Dis Child. 1968 Aug;43(230):410–414. doi: 10.1136/adc.43.230.410. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Glass M. R., Williams J. W., Butt W. R., Edwards R. L., London D. R. Basal serum prolactin values and responses to the administration of thyrotrophin releasing hormone (TRH) in women with amenorrhoea. Br J Obstet Gynaecol. 1976 Jun;83(6):495–501. doi: 10.1111/j.1471-0528.1976.tb00872.x. [DOI] [PubMed] [Google Scholar]
  7. Hoff W van't, Bicknell E. J. Congenital adrenal hyperplasia and diabetes mellitus in a woman aged 71 years. Acta Endocrinol (Copenh) 1972 Feb;69(2):329–334. doi: 10.1530/acta.0.0690329. [DOI] [PubMed] [Google Scholar]
  8. Horton R., Frasier S. D. Androstenedione and its conversion to plasma testosterone in congenital adrenal hyperplasia. J Clin Invest. 1967 Jun;46(6):1003–1009. doi: 10.1172/JCI105589. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Ishida H., Kukutani K., Imao S., Hirose K., Isurugi K. Pituitary-gonadal function in a female hermaphrodite with congenital adrenal hyperplasia. J Urol. 1976 Jul;116(1):130–131. doi: 10.1016/s0022-5347(17)58714-5. [DOI] [PubMed] [Google Scholar]
  10. Kirkland J., Kirkland R., Librik L., Clayton G. Serum gonadotropin levels in female adolescents with congenital adrenal hyperplasia. J Pediatr. 1974 Mar;84(3):411–414. doi: 10.1016/s0022-3476(74)80728-6. [DOI] [PubMed] [Google Scholar]
  11. Larsson-Cohn U., Johansson E. D., Kågedal B., Wallentin L. Serum FSH, LH and oestrone levels in postmenopausal patients on oestrogen therapy. Br J Obstet Gynaecol. 1978 May;85(5):367–372. doi: 10.1111/j.1471-0528.1978.tb14896.x. [DOI] [PubMed] [Google Scholar]
  12. Migeon C. J., Kenny F. M. Cortisol production rate. V. Congenital virilizing adrenal hyperplasia. J Pediatr. 1966 Nov;69(5):779–786. doi: 10.1016/s0022-3476(66)80124-5. [DOI] [PubMed] [Google Scholar]
  13. Morris R. A simple and economical method for the radioimmunoassay of cortisol in serum. Ann Clin Biochem. 1978 May;15(3):178–183. doi: 10.1177/000456327801500139. [DOI] [PubMed] [Google Scholar]
  14. Morris R., Leeson S. A. A comparison of two methods for the separate estimation of 11-deoxy and 11-oxygenated 17-hydroxycorticosteroids in urine. J Med Lab Technol. 1969 Jul;26(3):243–247. [PubMed] [Google Scholar]
  15. Mortimer C. H., Besser G. M., McNeilly A. S., Marshall J. C., Harsoulis P., Tunbridge W. M., Gomez-Pan A., Hall R. Luteinizing hormone and follicle stimulating hormone-releasing hormone test in patients with hypothalamic-pituitary-gonadal dysfunction. Br Med J. 1973 Oct 13;4(5884):73–77. doi: 10.1136/bmj.4.5884.73. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Pham-Huu-Trung M. T., Gourmelen M., Raux-Eurin M. C., Girard F. Pituitary-adrenal axis activity in treated congenital adrenal hyperplasia: static and dynamic studies. J Clin Endocrinol Metab. 1978 Aug;47(2):422–427. doi: 10.1210/jcem-47-2-422. [DOI] [PubMed] [Google Scholar]
  17. Rees L. H. ACTH, lipotrophin and MSH in health and disease. Clin Endocrinol Metab. 1977 Mar;6(1):137–153. doi: 10.1016/s0300-595x(77)80060-1. [DOI] [PubMed] [Google Scholar]
  18. Reiter E. O., Grumbach M. M., Kaplan S. L., Conte F. A. The response of pituitary gonadotropes to synthetic LRF in children with glucocorticoid-treated congenital adrenal hyperplasia: lack of effect of intrauterine and neonatal androgen excess. J Clin Endocrinol Metab. 1975 Feb;40(2):318–325. doi: 10.1210/jcem-40-2-318. [DOI] [PubMed] [Google Scholar]
  19. Richards G. E., Grumbach M. M., Kaplan S. L., Conte F. A. The effect of long acting glucocorticoids on menstrual abnormalities in patients with virilizing congenital adrenal hyperplasia. J Clin Endocrinol Metab. 1978 Dec;47(6):1208–1215. doi: 10.1210/jcem-47-6-1208. [DOI] [PubMed] [Google Scholar]
  20. Rudd B. T., Rayner P. H. Androgens levels in plasma and urine of patients with virilizing congenital adrenal hyperplasia. Proc R Soc Med. 1970 Oct;63(10):1039–1040. doi: 10.1177/003591577006301032. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Shaw R. W., Butt W. R., London D. R., Marshall J. C. Variation in response to synthetic luteinizing hormone--releasing hormone (LH-RH) at different phases of the same menstrual cycle in normal women. J Obstet Gynaecol Br Commonw. 1974 Aug;81(8):632–639. doi: 10.1111/j.1471-0528.1974.tb00530.x. [DOI] [PubMed] [Google Scholar]

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