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. 1981 May;57(667):294–296. doi: 10.1136/pgmj.57.667.294

Subarachnoid haemorrhage and the electrocardiogram - a review.

A D Harries
PMCID: PMC2424935  PMID: 6117845

Abstract

Electrocardiographic abnormalities occur in approximately 50% of patients with subarachnoid haemorrhage. The changes can resemble those of myocardial damage, although in most cases post-mortem studies show no macroscopic evidence of injury. Failure to appreciate this can lead to misdiagnosis of organic cardiac disease, cause delay in surgical treatment or even lead to inappropriate therapy. This review deals with the changes that may occur in the electrocardiogram, discusses the explanations put forward, and examines how this may influence future trends in management.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ananthachari M. D., Anto C. D. A study of ECG changes in 20 cases of subarachnoid haemorrhage. Indian Heart J. 1967 Apr;19(2):105–113. [PubMed] [Google Scholar]
  2. BURCH G. E., DEPASQUALE N., MALARET G. Selected problems in electrocardiography. Ann Intern Med. 1960 Mar;52:587–601. doi: 10.7326/0003-4819-52-3-587. [DOI] [PubMed] [Google Scholar]
  3. CROMPTON M. R. Hypothalamic lesions following the rupture of cerebral berry aneurysms. Brain. 1963 Jun;86:301–314. doi: 10.1093/brain/86.2.301. [DOI] [PubMed] [Google Scholar]
  4. CROPP G. J., MANNING G. W. Electrocardiographic changes simulating myocardial ischemia and infarction associated with spontaneous intracranial hemorrhage. Circulation. 1960 Jul;22:25–38. doi: 10.1161/01.cir.22.1.25. [DOI] [PubMed] [Google Scholar]
  5. Catovsky D., Sforza M. B. Phytohaemagglutinin in aplastic anaemia. Lancet. 1967 Nov 4;2(7523):991–992. doi: 10.1016/s0140-6736(67)90838-0. [DOI] [PubMed] [Google Scholar]
  6. Connor R. C. Heart damage associated with intracranial lesions. Br Med J. 1968 Jul 6;3(5609):29–31. doi: 10.1136/bmj.3.5609.8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Cruickshank J. M., Neil-Dwyer G., Lane J. The effect of oral propranolol upon the ECG changes occurring in subarachnoid haemorrhage. Cardiovasc Res. 1975 Mar;9(2):236–245. doi: 10.1093/cvr/9.2.236. [DOI] [PubMed] [Google Scholar]
  8. Cruickshank J. M., Neil-Dwyer G., Stott A. W. Possible role of catecholamines, corticosteroids, and potassium in production of electrocardiographic abnormalities associated with subarachnoid haemorrhage. Br Heart J. 1974 Jul;36(7):697–706. doi: 10.1136/hrt.36.7.697. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Doshi R., Neil-Dwyer G. A clinicopathological study of patients following a subarachnoid hemorrhage. J Neurosurg. 1980 Mar;52(3):295–301. doi: 10.3171/jns.1980.52.3.0295. [DOI] [PubMed] [Google Scholar]
  10. Doshi R., Neil-Dwyer G. Hypothalamic and myocardial lesions after subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry. 1977 Aug;40(8):821–826. doi: 10.1136/jnnp.40.8.821. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Dubo H., Park D. C., Pennington R. J., Kalbag R. M., Walton J. N. Serum-creatine-kinase in cases of stroke, head injury, and meningitis. Lancet. 1967 Oct 7;2(7519):743–748. doi: 10.1016/s0140-6736(67)91946-0. [DOI] [PubMed] [Google Scholar]
  12. Eisalo A., Peräsalo J., Halonen P. I. Electrocardiographic abnormalities and some laboratory findings in patients with subarachnoid haemorrhage. Br Heart J. 1972 Mar;34(3):217–226. doi: 10.1136/hrt.34.3.217. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Greenhoot J. H., Reichenbach D. D. Cardiac injury and subarachnoid hemorrhage. A clinical, pathological, and physiological correlation. J Neurosurg. 1969 May;30(5):521–531. doi: 10.3171/jns.1969.30.5.0521. [DOI] [PubMed] [Google Scholar]
  14. HOFFBRAND B. I., MORGAN B. D. FUNCTIONAL SIGNIFICANCE OF ELECTROCARDIOGRAPHIC CHANGES ASSOCIATED WITH SUBARACHNOID HAEMORRHAGE. Lancet. 1965 Apr 17;1(7390):844–845. doi: 10.1016/s0140-6736(65)91377-2. [DOI] [PubMed] [Google Scholar]
  15. Hunt D., McRae C., Zapf P. Electrocardiographic and serum enzyme change in subarachnoid hemorrhage. Am Heart J. 1969 Apr;77(4):479–488. doi: 10.1016/0002-8703(69)90157-4. [DOI] [PubMed] [Google Scholar]
  16. Jenkins J. S., Buckell M., Carter A. B., Westlake S. Hypothalamic-pituitary-adrenal function after subarachnoid haemorrhage. Br Med J. 1969 Dec 20;4(5685):707–709. doi: 10.1136/bmj.4.5685.707. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. KOSKELO P., PUNSAR S., SIPILAE W. SUBENDOCARDIAL HAEMORRHAGE AND E.C.G. CHANGES IN INTRACRANIAL BLEEDING. Br Med J. 1964 Jun 6;1(5396):1479–1480. doi: 10.1136/bmj.1.5396.1479. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. LEPESCHKIN E., MARCHET H., SCHROEDER G., WAGNER R., de PAULA E SILVA, RAAB W. Effect of epinephrine and norepinephrine on the electrocardiogram of 100 normal subjects. Am J Cardiol. 1960 May;5:594–603. doi: 10.1016/0002-9149(60)90124-7. [DOI] [PubMed] [Google Scholar]
  19. MELVILLE K. I., BLUM B., SHISTER H. E., SILVER M. D. CARDIAC ISCHEMIC CHANGES AND ARRHYTHMIAS INDUCED BY HYPOTHALAMIC STIMULATION. Am J Cardiol. 1963 Dec;12:781–791. doi: 10.1016/0002-9149(63)90281-9. [DOI] [PubMed] [Google Scholar]
  20. Neil-Dwyer G., Walter P., Cruickshank J. M., Doshi B., O'Gorman P. Effect of propranolol and phentolamine on myocardial necrosis after subarachnoid haemorrhage. Br Med J. 1978 Oct 7;2(6143):990–992. doi: 10.1136/bmj.2.6143.990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. SHUSTER S. The electrocardiogram in subarachnoid haemorrhage. Br Heart J. 1960 Jun;22:316–320. doi: 10.1136/hrt.22.3.316. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Selye H. The evolution of the stress concept. Stress and cardiovascular disease. Am J Cardiol. 1970 Sep;26(3):289–299. doi: 10.1016/0002-9149(70)90796-4. [DOI] [PubMed] [Google Scholar]

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