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. 1981 Apr;57(666):235–237. doi: 10.1136/pgmj.57.666.235

Symptomatic hypopituitarism revealing a primary empty sella turcica.

B Velkeniers, D Desir, D Manicourt, F Chanoine, M Dupont, G Copinschi
PMCID: PMC2424994  PMID: 7291102

Abstract

A 64-year-old nulliparous woman presented with clinical signs of thyroid and adrenocortical insufficiency. Subsequent hormonal investigations demonstrated a failure of all anterior pituitary functions. Pneumotomo-encephalography revealed a large arachnoid herniation, leading to the diagnosis of primary empty sella turcica syndrome with secondary panhypopituitarism. This unusual observation emphasizes the necessity of ruling out an empty sella turcica syndrome in patients with pituitary insufficiency.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bar R. S., Mazzaferri E. L., Malarkey W. B. Primary empty sella, galactorrhea, hyperprolactinemia and renal tubular acidosis. Am J Med. 1975 Dec;59(6):863–866. doi: 10.1016/0002-9343(75)90473-8. [DOI] [PubMed] [Google Scholar]
  2. Bergland R. M., Ray B. S., Torack R. M. Anatomical variations in the pituitary gland and adjacent structures in 225 human autopsy cases. J Neurosurg. 1968 Feb;28(2):93–99. doi: 10.3171/jns.1968.28.2.0093. [DOI] [PubMed] [Google Scholar]
  3. Berke J. P., Buxton L. F., Kokmen E. The 'empty' sella. Neurology. 1975 Dec;25(12):1137–1143. doi: 10.1212/wnl.25.12.1137. [DOI] [PubMed] [Google Scholar]
  4. Bernasconi V., Giovanelli M. A., Papo I. Primary empty sella. J Neurosurg. 1972 Feb;36(2):157–161. doi: 10.3171/jns.1972.36.2.0157. [DOI] [PubMed] [Google Scholar]
  5. Brisman R., Hughes J. E., Holub D. A. Endocrine function in nineteen patients with empty sella syndrome. J Clin Endocrinol Metab. 1972 Mar;34(3):570–573. doi: 10.1210/jcem-34-3-570. [DOI] [PubMed] [Google Scholar]
  6. Bryner J. R., Greenblatt R. B. Primary empty sella syndrome with elevated serum prolactin. Obstet Gynecol. 1977 Sep;50(3):375–380. [PubMed] [Google Scholar]
  7. Cupps T. R., Woolf P. D. Primary empty sella syndrome with panhypopituitarism, diabetes insipidus, and visual field defects. Acta Endocrinol (Copenh) 1978 Nov;89(3):445–460. doi: 10.1530/acta.0.0890445. [DOI] [PubMed] [Google Scholar]
  8. Faglia G., Beck-Peccoz P., Ambrosi B., Ferrari C., Giovanelli M. The empty-sella syndrome. Lancet. 1973 Jul 21;2(7821):149–149. doi: 10.1016/s0140-6736(73)93091-2. [DOI] [PubMed] [Google Scholar]
  9. Ganguly A., Stanchfield J. B., Roberts T. S., West C. D., Tyler F. H. Cushing's syndrome in a patient with an empty sella turcica and a microadenoma of the adenohypophysis. Am J Med. 1976 Feb;60(2):306–309. doi: 10.1016/0002-9343(76)90442-3. [DOI] [PubMed] [Google Scholar]
  10. Jordan R. M., Kendall J. W., Kerber C. W. The primary empty sella syndrome: analysis of the clinical characteristics, radiographic features, pituitary function and cerebrospinal fluid adenohypophysial hormone concentrations. Am J Med. 1977 Apr;62(4):569–580. doi: 10.1016/0002-9343(77)90420-x. [DOI] [PubMed] [Google Scholar]
  11. Matisonn R., Pimstone B. Diabetes insipidus associated with an empty sella turcica. Postgrad Med J. 1973 Apr;49(570):274–276. doi: 10.1136/pgmj.49.570.274. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Molitch M. E., Hieshima G. B., Marcovitz S., Jackson I. M., Wolpert S. Coexisting primary empty sella syndrome and acromegally. Clin Endocrinol (Oxf) 1977 Sep;7(3):261–263. doi: 10.1111/j.1365-2265.1977.tb01323.x. [DOI] [PubMed] [Google Scholar]
  13. Mortara R., Norrell H. Consequences of a deficient sellar diaphragm. J Neurosurg. 1970 May;32(5):565–573. doi: 10.3171/jns.1970.32.5.0565. [DOI] [PubMed] [Google Scholar]
  14. Neelon F. A., Goree J. A., Lebovitz H. E. The primary empty sella: clinical and radiographic characteristics and endocrine function. Medicine (Baltimore) 1973 Jan;52(1):73–92. [PubMed] [Google Scholar]
  15. Weisberg L. A., Zimmerman E. A., Frantz A. G. Diagnosis and evaluation of patients with an enlarged sella turcica. Am J Med. 1976 Nov;61(5):590–596. doi: 10.1016/0002-9343(76)90136-4. [DOI] [PubMed] [Google Scholar]

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