Abstract
Cimetidine has been reported as suppressing the excess parathyroid hormone secretion and hypercalcaemia seen in hyperparathyroidism. A case of primary hyperparathyroidism is described, in which the level of circulating parathyroid hormone and hypercalcaemia remain entirely unaffected by cimetidine. The drug is implicated in the management of primary hyperparathyroidism unsuitable for surgery, but present evidence, as reviewed, is insufficient to recommend the use of cimetidine in this way.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- MacGregor C. A. Cimetidine in hyperparathyroidism. Lancet. 1980 May 3;1(8175):980–981. [PubMed] [Google Scholar]
- McCarthy D. M., Peikin S. R., Lopatin R. N., Long B. W., Spiegel A., Marx S., Brennan M. Hyperparathyroidism--a reversible cause of cimetidine-resistant gastric hypersecretion. Br Med J. 1979 Jun 30;1(6180):1765–1766. doi: 10.1136/bmj.1.6180.1765. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sherwood J. K., Ackroyd F. W., Garcia M. Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism. Lancet. 1980 Mar 22;1(8169):616–620. doi: 10.1016/s0140-6736(80)91117-4. [DOI] [PubMed] [Google Scholar]