Abstract
The clinical histories of two patients are presented, who both developed haemorrhagic anuria after a short course of therapy with the carbonic anhydrase inhibitor, acetazolamide (Diamox). The clinical findings, in particular the radiological changes, are illustrated in this potentially fatal condition. The therapeutic success of immediate relief of the ureteric obstruction is emphasized and it is hoped that this report will act as a reminder of the importance of this agent as a cause of anuria.
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- ARNEIL G. C. Twenty-nine children with sulphonamide haematuria. Lancet. 1958 Apr 19;1(7025):826–827. doi: 10.1016/s0140-6736(58)91743-4. [DOI] [PubMed] [Google Scholar]
- BERTINO J. R., RODMAN T., MYERSON R. M. Thrombocytopenia and renal lesions associated with acetazoleamide (diamox) therapy. AMA Arch Intern Med. 1957 Jun;99(6):1006–1008. doi: 10.1001/archinte.1957.00260060164013. [DOI] [PubMed] [Google Scholar]
- Hackett P. H., Rennie D., Levine H. D. The incidence, importance, and prophylaxis of acute mountain sickness. Lancet. 1976 Nov 27;2(7996):1149–1155. doi: 10.1016/s0140-6736(76)91677-9. [DOI] [PubMed] [Google Scholar]
- Howlett S. A. Renal failure associated with acetazolamide therapy for glaucoma. South Med J. 1975 Apr;68(4):504–506. doi: 10.1097/00007611-197504000-00026. [DOI] [PubMed] [Google Scholar]