Abstract
A rapid computational method for maximum likelihood estimation of most-probable-number values, incorporating a modified Newton-Raphson method, is presented. The method offers a much greater reliability for the most-probable-number estimate of total viable bacteria, i.e., those capable of growth in laboratory media.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- COCHRAN W. G. Estimation of bacterial densities by means of the "most probable number". Biometrics. 1950 Jun;6(2):105–116. [PubMed] [Google Scholar]
- Halvorson H. O., Ziegler N. R. Application of Statistics to Problems in Bacteriology: III. A Consideration of the Accuracy of Dilution Data Obtained by Using Several Dilutions. J Bacteriol. 1933 Dec;26(6):559–567. doi: 10.1128/jb.26.6.559-567.1933. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Koch A. L. Estimation of the most probable number with a programable pocket calculator. Appl Environ Microbiol. 1982 Feb;43(2):488–490. doi: 10.1128/aem.43.2.488-490.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MORAN P. A. The dilution assay of viruses. J Hyg (Lond) 1954 Jun;52(2):189–193. doi: 10.1017/s002217240002739x. [DOI] [PMC free article] [PubMed] [Google Scholar]