Abstract
Candida albicans peritonitis developed in a 48-year-old man with a perforated gastric ulcer who subsequently was treated with intravenous amphotericin B. The drug penetrated well into the inflamed peritoneal cavity and eradicated the organism from the peritoneal fluid. Nevertheless, at post-mortem, Candida organisms were demonstrated in a gall-bladder empyema and within the gall-bladder wall. Because intra-abdominal organs may be involved in Candida peritonitis, the use of high dose amphotericin B administered either intravenously, intraperitoneally, or both intravenously and intraperitoneally is recommended.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bayer A. S., Blumenkrantz M. J., Montgomerie J. Z., Galpin J. E., Coburn J. W., Guze L. B. Candida peritonitis. Report of 22 cases and review of the English literature. Am J Med. 1976 Dec;61(6):832–840. doi: 10.1016/0002-9343(76)90407-1. [DOI] [PubMed] [Google Scholar]
- Bennett J. E. Chemotherapy of systemic mycoses (second of two parts). N Engl J Med. 1974 Feb 7;290(6):320–323. doi: 10.1056/NEJM197402072900607. [DOI] [PubMed] [Google Scholar]
- Bortolussi R. A., MacDonald M. R., Bannatyne R. M., Arbus G. S. Treatment of Candida peritonitis by peritoneal lavage with amphotericin B. J Pediatr. 1975 Dec;87(6 Pt 1):987–988. doi: 10.1016/s0022-3476(75)80925-5. [DOI] [PubMed] [Google Scholar]
- Feldman H. A., Hamilton J. D., Gutman R. A. Amphotericin B therapy in an anephric patient. Antimicrob Agents Chemother. 1973 Sep;4(3):302–305. doi: 10.1128/aac.4.3.302. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GREEN W. R., BENNETT J. E., GOOS R. D. OCULAR PENETRATION OF AMPHOTERICIN B: A REPORT OF LABORATORY STUDIES AND A CASE REPORT OF POSTSURGICAL CEPHALOSPORIUM ENDOPHTHALMITIS. Arch Ophthalmol. 1965 Jun;73:769–775. doi: 10.1001/archopht.1965.00970030771004. [DOI] [PubMed] [Google Scholar]
- Montemartini C., Specchia G., Dander B. Peritonitis caused by candida albicans. Digestion. 1970;3(6):368–371. doi: 10.1159/000197057. [DOI] [PubMed] [Google Scholar]
- Reeves K. O., Ripepi A. C., Carter R. E., Jr, Williams T. W., Jr Candida peritonitis in a quadriplegic: treatment with amphotericin B. South Med J. 1972 Mar;65(3):325–328. doi: 10.1097/00007611-197203000-00016. [DOI] [PubMed] [Google Scholar]