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. 1978 Mar;54(629):149–155. doi: 10.1136/pgmj.54.629.149

Essential fatty acids and the vulnerability of the artery during growth.

K P Ball, M A Cranford, A G Hassam, J P Rivers
PMCID: PMC2425183  PMID: 349533

Abstract

Essential fatty acids not only control blood lipid levels, but are the precursors of prostaglandins responsible for regulation of platelet aggregation. Dietary deficiency of essential fatty acids may play an important role in the development of coronary heart disease, particularly during the early growth period.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BOETTCHER C. J. CHEMICAL CONSTITUENTS OF HUMAN ATHEROSCLEROTIC LESIONS. Proc R Soc Med. 1964 Sep;57:792–795. doi: 10.1177/003591576405700911. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Brenner R. R. The oxidative desaturation of unsaturated fatty acids in animals. Mol Cell Biochem. 1974 Mar 8;3(1):41–52. doi: 10.1007/BF01660076. [DOI] [PubMed] [Google Scholar]
  3. Crawford M. A., Hassam A. G., Hall B. M. Metabolism of essential fatty acids in the human fetus and neonate. Nutr Metab. 1977;21 (Suppl 1):187–188. doi: 10.1159/000176156. [DOI] [PubMed] [Google Scholar]
  4. Hassam A. G., Rivers J. P., Crawford M. A. Metabolism of gamma-linolenic acid in essential fatty acid-deficient rats. J Nutr. 1977 Apr;107(4):519–524. doi: 10.1093/jn/107.4.519. [DOI] [PubMed] [Google Scholar]
  5. Hassam A. G., Sinclair A. J., Crawford M. A. The incorporation of orally fed radioactive gamma-linolenic acid and linoleic acid into the liver and brain lipids of suckling rats. Lipids. 1975 Jul;10(7):417–420. [PubMed] [Google Scholar]
  6. Hassma A. G., Crawford M. A. The differential incorporation of labelled linoleic, gamma-linolenic, dihomo-gamma-linolenic and arachidonic acids into the developing rat brain. J Neurochem. 1976 Oct;27(4):967–968. doi: 10.1111/j.1471-4159.1976.tb05163.x. [DOI] [PubMed] [Google Scholar]
  7. Louw M. E., Du Plessis J. P., Van den Berg A. S., Fellingham S. A. Intercorrelation study of dietary and biochemical data from schoolchildren in the Pretoria area. S Afr Med J. 1969 Dec 20;43(50):1516–1527. [PubMed] [Google Scholar]
  8. McKinney B., Crawford M. A. Fibrosis in guineapig heart produced by plantain diet. Lancet. 1965 Oct 30;2(7418):880–882. doi: 10.1016/s0140-6736(65)92506-7. [DOI] [PubMed] [Google Scholar]
  9. Moncada S., Gryglewski R., Bunting S., Vane J. R. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature. 1976 Oct 21;263(5579):663–665. doi: 10.1038/263663a0. [DOI] [PubMed] [Google Scholar]
  10. Pikaar N. A., Fernandes J. Influence of different types of dietary fat on the fatty acid composition of some serum lipid fractions in infants and children. Am J Clin Nutr. 1966 Sep;19(3):194–204. doi: 10.1093/ajcn/19.3.194. [DOI] [PubMed] [Google Scholar]
  11. SHAPER A. G., JONES K. W. Serum-cholesterol in camelherding nomads. Lancet. 1962 Dec 22;2(7269):1305–1307. doi: 10.1016/s0140-6736(62)90852-8. [DOI] [PubMed] [Google Scholar]
  12. SMITH E. B. THE INFLUENCE OF AGE AND ATHEROSCLEROSIS ON THE CHEMISTRY OF AORTIC INTIMA. 1. THE LIPIDS. J Atheroscler Res. 1965 Mar-Apr;5(2):224–240. doi: 10.1016/s0368-1319(65)80064-3. [DOI] [PubMed] [Google Scholar]
  13. Sinclair A. J. Incorporation of radioactive polyunsaturated fatty acids into liver and brain of developing rat. Lipids. 1975 Mar;10(3):175–184. doi: 10.1007/BF02534156. [DOI] [PubMed] [Google Scholar]
  14. Sun G. Y., Go J., Sun A. Y. Induction of essential fatty acid deficiency in mouse brain: effects of fat deficient diet upon acyl group composition of myelin and synaptosome-rich fractions during development and maturation. Lipids. 1974 Jul;9(7):450–454. doi: 10.1007/BF02534270. [DOI] [PubMed] [Google Scholar]
  15. VAN DORPD, BEERTHUIS R. K., NUGTEREN D. H., VONKEMAN H. ENZYMATIC CONVERSION OF ALL-CIS-POLYUNSATURATED FATTY ACIDS INTO PROSTAGLANDINS. Nature. 1964 Aug 22;203:839–841. doi: 10.1038/203839a0. [DOI] [PubMed] [Google Scholar]
  16. van Dorp D. A. Essential fatty acid metabolism. Proc Nutr Soc. 1975 Dec;34(3):279–286. doi: 10.1079/pns19750050. [DOI] [PubMed] [Google Scholar]

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