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. 1978 Apr;54(630):261–264. doi: 10.1136/pgmj.54.630.261

Advanced carcinoma of the prostate- does the pre-treatment Leydig cell function determine the response to orchidectomy?

A L Houghton, H S Jacobs
PMCID: PMC2425256  PMID: 662791

Abstract

In a study of twenty patients there was no support for the hypothesis that the response to orchidectomy of patients with advanced prostatic cancer depends on pre-operative Leydig cell function. The only significant prognostic factor was the histological grade of the primary tumour.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baier H., Biro G., Weinges K. F. Serum levels of FSH, LH and testosterone in human males. Horm Metab Res. 1974 Nov;6(6):514–516. doi: 10.1055/s-0028-1093800. [DOI] [PubMed] [Google Scholar]
  2. Bramble F. J., Jacobs H. S. Letter: Hormones, elderly testes, and carcinoma of the prostate. Br Med J. 1975 Aug 2;3(5978):307–307. doi: 10.1136/bmj.3.5978.307-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Burge P. D. Subcapsular orchidectomy--an effective operation? Proc R Soc Med. 1976 Sep;69(9):663–664. [PMC free article] [PubMed] [Google Scholar]
  4. Habib F. K., Lee I. R., Stitch S. R., Smith P. H. Androgen levels in the plasma and prostatic tissues of patients with benign hypertrophy and carcinoma of the prostate. J Endocrinol. 1976 Oct;71(1):99–107. doi: 10.1677/joe.0.0710099. [DOI] [PubMed] [Google Scholar]
  5. Horton R., Hsieh P., Barberia J., Pages L., Cosgrove M. Altered blood androgens in elderly men with prostate hyperplasia. J Clin Endocrinol Metab. 1975 Oct;41(4):793–796. doi: 10.1210/jcem-41-4-793. [DOI] [PubMed] [Google Scholar]
  6. Huggins C. EFFECT OF ORCHIECTOMY AND IRRADIATION ON CANCER OF THE PROSTATE. Ann Surg. 1942 Jun;115(6):1192–1200. doi: 10.1097/00000658-194206000-00030. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Jacobs H. S., Lawton N. F. Radioimmunoassay and saturation analysis. Pituitary and placental glycopeptide hormones. Br Med Bull. 1974 Jan;30(1):55–61. doi: 10.1093/oxfordjournals.bmb.a071168. [DOI] [PubMed] [Google Scholar]
  8. Robinson M. R., Thomas B. S. Effect of hormonal therapy on plasma testosterone levels in prostatic carcinoma. Br Med J. 1971 Nov 13;4(5784):391–394. doi: 10.1136/bmj.4.5784.391. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Shearer R. J., Hendry W. F., Sommerville I. F., Fergusson J. D. Plasma testosterone: an accurate monitor of hormone treatment in prostatic cancer. Br J Urol. 1973 Dec;45(6):668–677. doi: 10.1111/j.1464-410x.1973.tb12238.x. [DOI] [PubMed] [Google Scholar]
  10. Stearns E. L., MacDonnell J. A., Kaufman B. J., Padua R., Lucman T. S., Winter J. S., Faiman C. Declining testicular function with age. Hormonal and clinical correlates. Am J Med. 1974 Nov;57(5):761–766. doi: 10.1016/0002-9343(74)90850-x. [DOI] [PubMed] [Google Scholar]

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