Abstract
During the course of an obscure illness in a teenage girl it was eventually realized that the diagnosis was 'epidemic neuromyasthenia'. The illness which occurred between February and September 1976 was characterized by fatigue, pallor, headache, nuchal pain, alterations in mentation, dizziness, nausea and vomiting, paraesthesiae, weakness and heaviness of limbs, and a prolonged relapsing course. Investigation brought to light fourteen patients with similar symptoms--twelve female and two male. In view of the shortcomings of retrospective enquiries, especially those involving the assessment of notes made by other people, and the problem of trying to define a nonfatal illness with protean symptoms, many of a nonspecific nature, with few physical findings and negative laboratory studies, caution is necessary. Under these circumstances it is claimed on clinical epidemiological evidence that a diagnosis of 'epidemic neuromyasthenia' could be sustained confidently in three patients and probably in a fourth. Six patients were considered possible cases and four were rejected.
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Selected References
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- ACHESON E. D. The clinical syndrome variously called benign myalgic encephalomyelitis, Iceland disease and epidemic neuromyasthenia. Am J Med. 1959 Apr;26(4):569–595. doi: 10.1016/0002-9343(59)90280-3. [DOI] [PubMed] [Google Scholar]
- Graybill J. R., Silva J., Jr, O'Brien M. S., Reinarz J. A. Epidemic neuromyasthenia. A syndrome or disease? JAMA. 1972 Mar 13;219(11):1440–1443. [PubMed] [Google Scholar]
- Innes S. G. Encephalomyelitis resembling benign myalgic encephalomyelitis. Lancet. 1970 May 9;1(7654):969–971. doi: 10.1016/s0140-6736(70)91097-4. [DOI] [PubMed] [Google Scholar]
- McEvedy C. P., Beard A. W. Royal Free epidemic of 1955: a reconsideration. Br Med J. 1970 Jan 3;1(5687):7–11. doi: 10.1136/bmj.1.5687.7. [DOI] [PMC free article] [PubMed] [Google Scholar]