Abstract
In a study of 17 subjects plasma-thyroxine-binding globulin and plasma thyroxine concentrations rose during a high altitude trek. An early and sustained rise in plasma reverse triiodothyronine occurred independently of changes in plasma thyroxine and was probably related to physical exertion. Similar changes in thyroid function were found in subjects most affected and least affected by acute mountain sickness.
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Selected References
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- Bradwell A. R. Birmingham Medical Research Expeditionary Society 1977 Expedition: serum and urine proteins during a high altitude trek. Postgrad Med J. 1979 Jul;55(645):478–482. doi: 10.1136/pgmj.55.645.478. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bradwell A. R., Burnett D., Ramsden D. B., Burr W. A., Prince H. P., Hoffenberg R. Preparation of a monospecific antiserum to thyroxine binding globulin for its quantitation by rocket immunoelectrophoresis. Clin Chim Acta. 1976 Sep 20;71(3):501–510. doi: 10.1016/0009-8981(76)90102-9. [DOI] [PubMed] [Google Scholar]
- Burr W. A., Black E. G., Griffiths R. S., Hoffenberg R. Serum triiodothyronine and reverse triiodothyronine concentrations after surgical operation. Lancet. 1975 Dec 27;2(7948):1277–1279. doi: 10.1016/s0140-6736(75)90612-1. [DOI] [PubMed] [Google Scholar]
- Chopra I. J. An assessment of daily production and significance of thyroidal secretion of 3, 3', 5'-triiodothyronine (reverse T3) in man. J Clin Invest. 1976 Jul;58(1):32–40. doi: 10.1172/JCI108456. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Griffiths R. S., Black E. G., Hoffenberg R. Measurement of serum 3,3',5'-(reverse) T3, with comments on its derivation. Clin Endocrinol (Oxf) 1976 Nov;5(6):679–685. doi: 10.1111/j.1365-2265.1976.tb03871.x. [DOI] [PubMed] [Google Scholar]
- Kotchen T. A., Mougey E. H., Hogan R. P., Boyd A. E., 3rd, Pennington L. L., Mason J. W. Thyroid responses to simulated altitude. J Appl Physiol. 1973 Feb;34(2):165–168. doi: 10.1152/jappl.1973.34.2.165. [DOI] [PubMed] [Google Scholar]
- Nicod P., Burger A., Staeheli V., Vallotton M. B. Radioimmunoassay for 3,3',5'-triiodo-L-thyronine in unextracted serum: method and clinical results. J Clin Endocrinol Metab. 1976 May;42(5):823–829. doi: 10.1210/jcem-42-5-823. [DOI] [PubMed] [Google Scholar]
- Rastogi G. K., Malhotra M. S., Srivastava M. C., Sawhney R. C., Dua G. L., Sridharan K., Hoon R. S., Singh I. Study of the pituitary-thyroid functions at high altitude in man. J Clin Endocrinol Metab. 1977 Mar;44(3):447–452. doi: 10.1210/jcem-44-3-447. [DOI] [PubMed] [Google Scholar]
- Surks M. I., Beckwitt H. J., Chidsey C. A. Changes in plasma thyroxine concentration and metabolism, catecholamine excretion and basal oxygen consumption in man during acute exposure to high altitude. J Clin Endocrinol Metab. 1967 Jun;27(6):789–799. doi: 10.1210/jcem-27-6-789. [DOI] [PubMed] [Google Scholar]
- Surks M. I. Elevated PBI, free thyroxine, and plasma protein concentration in man at high altitude. J Appl Physiol. 1966 Jul;21(4):1185–1190. doi: 10.1152/jappl.1966.21.4.1185. [DOI] [PubMed] [Google Scholar]