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. 1979 Sep;55(647):648–652. doi: 10.1136/pgmj.55.647.648

Evaluation of vaginal antifungal formulations in vivo.

R J McRipley, P J Erhard, R A Schwind, R R Whitney
PMCID: PMC2425650  PMID: 392480

Abstract

Relatively simple and rapid procedures have been developed for evaluating the local efficacy of vaginal antifungal agents in vivo in a vaginal candidiasis model in ovariectomized rats. The results of this investigation indicate that the model and methods described are quite suitable for screening potential antifungal substances and for assessing the chemotherapeutic effectiveness of new antifungal agents and formulations before carrying out clinical studies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Polak A. Synergism of polyene antibiotics with 5-fluorocytosine. Chemotherapy. 1978;24(1):2–16. doi: 10.1159/000237753. [DOI] [PubMed] [Google Scholar]
  2. TASCHDJIAN C. L., REISS F., KOZINN P. J. Experimental vaginal candidiasis in mice; its implications for superficial candidiasis in humans. J Invest Dermatol. 1960 Feb;34:89–94. [PubMed] [Google Scholar]
  3. Wildfeuer A. Die Chemotherapie der vaginalen Trichomoniasis und Candidosis der Maus. Arzneimittelforschung. 1974 Jun;24(6):937–943. [PubMed] [Google Scholar]

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