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. 1980 Apr;56(654):236–237. doi: 10.1136/pgmj.56.654.236

Beta-adrenoceptor-blocking drugs, growth hormone and acromegaly.

J Feely
PMCID: PMC2425903  PMID: 7433322

Abstract

Chronic treatment with oxprenolol or propranolol in active hypertensive patients was associated with elevation of serum growth hormone (GH). Propranolol, 80 mg orally, caused a marked rise in GH in 3 of 4 acromegalic patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Coutant G., Vandeweghe M., Vermeulen A. Comparison of TRF, propranolol-glucagon, insulin and glucose stimulation tests in acromegaly. Horm Metab Res. 1977 Jan;9(1):17–21. doi: 10.1055/s-0028-1093576. [DOI] [PubMed] [Google Scholar]
  2. Cryer P. E., Daughaday W. H. Adrenergic modulation of growth hormone secretion in acromegaly: alpha- and beta-adrenergic blockade produce qualitatively normal responses but no effect on L-dopa suppresion. J Clin Endocrinol Metab. 1977 May;44(5):977–979. doi: 10.1210/jcem-44-5-977. [DOI] [PubMed] [Google Scholar]
  3. Cryer P. E., Daughaday W. H. Regulation of growth hormone secretion in acromegaly. J Clin Endocrinol Metab. 1969 Mar;29(3):386–393. doi: 10.1210/jcem-29-3-386. [DOI] [PubMed] [Google Scholar]
  4. Day J. L., Simpson N., Metcalfe J., Page R. L. Metabolic consequences of atenolol and propranolol in treatment of essential hypertension. Br Med J. 1979 Jan 13;1(6156):77–80. doi: 10.1136/bmj.1.6156.77. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Goldfine I. D. Medical treatment of acromegaly. Annu Rev Med. 1978;29:407–415. doi: 10.1146/annurev.me.29.020178.002203. [DOI] [PubMed] [Google Scholar]
  6. Imura H., Kato Y., Ikeda M., Morimoto M., Yawata M. Effect of adrenergic-blocking or -stimulating agents on plasma growth hormone, immunoreactive insulin, and blood free fatty acid levels in man. J Clin Invest. 1971 May;50(5):1069–1079. doi: 10.1172/JCI106578. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Lee P. A., Thompson R. G., Blizzard R. M. Relationship of the adrenergic nervous system and growth hormone release in normal adults and children with various growth disorders. Metabolism. 1974 Jul;23(7):595–601. doi: 10.1016/s0026-0495(74)80019-3. [DOI] [PubMed] [Google Scholar]
  8. Maclaren N. K., Taylor G. E., Raiti S. Propranolol-augmented, exercise-induced human growth hormone release. Pediatrics. 1975 Nov;56(5):804–807. [PubMed] [Google Scholar]
  9. Martins J. B., Kerber R. E., Sherman B. M., Marcus M. L., Ehrhardt J. C. Cardiac size and function in acromegaly. Circulation. 1977 Nov;56(5):863–869. doi: 10.1161/01.cir.56.5.863. [DOI] [PubMed] [Google Scholar]
  10. Sherman B. M., Harris C. E., Schlechte J., Duello T. M., Halmi N. S., VanGilder J., Chapler F. K., Granner D. K. Pathogenesis of prolactin-secreting pituitary adenomas. Lancet. 1978 Nov 11;2(8098):1019–1021. doi: 10.1016/s0140-6736(78)92339-5. [DOI] [PubMed] [Google Scholar]

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