Abstract
Proteolytic mutants were isolated from toxigenic strains of Clostridium botulinum type E after several transfers. When these cultures were plated on blood agar, almost all of the colonies obtained were proteolytic, and there were fewer toxigenic colonies than nontoxigenic colonies. The proteolytic mutants and nonproteolytic original strains were different in their biological properties.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- DOLMAN C. E. Recent observations on type E botulism. Can J Public Health. 1957 May;48(5):187–198. [PubMed] [Google Scholar]
- DasGupta B. R. Activation of Clostridium botulinum type B toxin by an endogenous enzyme. J Bacteriol. 1971 Dec;108(3):1051–1057. doi: 10.1128/jb.108.3.1051-1057.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- ERLANGER B. F., KOKOWSKY N., COHEN W. The preparation and properties of two new chromogenic substrates of trypsin. Arch Biochem Biophys. 1961 Nov;95:271–278. doi: 10.1016/0003-9861(61)90145-x. [DOI] [PubMed] [Google Scholar]
- Lee W. H., Riemann H. Correlation of toxic and non-toxic strains of Clostridium botulinum by DNA composition and homology. J Gen Microbiol. 1970 Jan;60(1):117–123. doi: 10.1099/00221287-60-1-117. [DOI] [PubMed] [Google Scholar]
- Oishi I., Okada T., Sakaguchi G. Responses of Clostridium botulinum type B and E progenitor toxins to some clostridial sulfhydryl-dependent proteases. Jpn J Med Sci Biol. 1975 Jun;28(3):157–164. doi: 10.7883/yoken1952.28.157. [DOI] [PubMed] [Google Scholar]