Abstract
Ninety-one subjects with uncomplicated essential hypertension were admitted to hospital. They received a diet with a fixed amount of sodium (55 mmol/day), without calorie restriction. Blood pressure was measured at 2-hr intervals and averaged for each day. In patients who apparently adhered to a low salt diet before admission (group I), BP dropped 5 mmHg during the first 24 hr and then remained stable. In patients who previously ingested more salt (group II) a similar drop in pressure occurred during the first day, but pressure declined another 6 mmHg during the second day, to stabilize thereafter. Both neurovegetative and sodium-dependent factors appear to contribute to the decrease in BP while the patient is in hospital.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Epstein M., Hollenberg N. K. Age as a determinant of renal sodium conservation in normal man. J Lab Clin Med. 1976 Mar;87(3):411–417. [PubMed] [Google Scholar]
- Freis E. D. Salt, volume and the prevention of hypertension. Circulation. 1976 Apr;53(4):589–595. doi: 10.1161/01.cir.53.4.589. [DOI] [PubMed] [Google Scholar]
- ISAACSON L. C., MODLIN M., JACKSON W. P. Sodium intake and hypertension. Lancet. 1963 Apr 27;1(7287):946–946. doi: 10.1016/s0140-6736(63)91717-3. [DOI] [PubMed] [Google Scholar]
- Morgan T., Adam W., Gillies A., Wilson M., Morgan G., Carney S. Hypertension treated by salt restriction. Lancet. 1978 Feb 4;1(8058):227–230. doi: 10.1016/s0140-6736(78)90479-8. [DOI] [PubMed] [Google Scholar]
- Parijs J., Joossens J. V., Van der Linden L., Verstreken G., Amery A. K. Moderate sodium restriction and diuretics in the treatment of hypertension. Am Heart J. 1973 Jan;85(1):22–34. doi: 10.1016/0002-8703(73)90522-x. [DOI] [PubMed] [Google Scholar]
- Prior I. A., Evans J. G., Harvey H. P., Davidson F., Lindsey M. Sodium intake and blood pressure in two Polynesian populations. N Engl J Med. 1968 Sep 5;279(10):515–520. doi: 10.1056/NEJM196809052791004. [DOI] [PubMed] [Google Scholar]
- van Brummelen P., Schalekamp M., de Graeff J. Influence of sodium intake on hydrochlorothiazide-induced changes in blood pressure, serum electrolytes, renin and aldosterone in essential hypertension. Acta Med Scand. 1978;204(3):151–157. doi: 10.1111/j.0954-6820.1978.tb08417.x. [DOI] [PubMed] [Google Scholar]
