Abstract
A Caucasian class F diabetic developed features suggestive of adrenocortical insufficiency during the second half of pregnancy. Serial biochemical and hormonal studies confirmed a diagnosis of progressive primary adrenal failure. Replacement therapy was introduced at 31 weeks' gestation and the pregnancy ended successfully 6 weeks later. Addison's disease is another autoimmune disorder that may occur in association with diabetic pregnancy.
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Selected References
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- Becker R. A., Hayashi R. H., Franks R. C., Speroff L. Effects of positional change and sodium balance on the renin-angiotensin-aldosterone system, big renin and prostaglandins in normal pregnancy. J Clin Endocrinol Metab. 1978 Mar;46(3):467–472. doi: 10.1210/jcem-46-3-467. [DOI] [PubMed] [Google Scholar]
- COPE C. L., BLACK E. The hydrocortisone production in late pregnancy. J Obstet Gynaecol Br Emp. 1959 Jun;66:404–408. doi: 10.1111/j.1471-0528.1959.tb02048.x. [DOI] [PubMed] [Google Scholar]
- Christlieb A. R. Renin-angiotensin-aldosterone system in diabetes mellitus. Diabetes. 1976;25(2 Suppl):820–825. [PubMed] [Google Scholar]
- Christy M., Deckert T., Nerup J. Immunity and autoimmunity in diabetes mellitus. Clin Endocrinol Metab. 1977 Jul;6(2):305–332. doi: 10.1016/s0300-595x(77)80040-6. [DOI] [PubMed] [Google Scholar]
- Gamlen T. R., Aynsley-Green A., Irvine W. J., McCallum C. J. Immunological studies in the neonate of a mother with Addison's disease and diabetes mellitus. Clin Exp Immunol. 1977 Apr;28(1):192–195. [PMC free article] [PubMed] [Google Scholar]
- Irvine W. J., McCallum C. J., Gray R. S., Campbell C. J., Duncan L. J., Farquhar J. W., Vaughan H., Morris P. J. Pancreatic islet-cell antibodies in diabetes mellitus correlated with the duration and type of diabetes, coexistent autoimmune disease, and HLA type. Diabetes. 1977 Feb;26(2):138–147. doi: 10.2337/diab.26.2.138. [DOI] [PubMed] [Google Scholar]
- OSLER M., PEDERSEN J. Pregnancy in a patient with Addison's disease and diabetes mellitus. Acta Endocrinol (Copenh) 1962 Sep;41:79–87. doi: 10.1530/acta.0.0410079. [DOI] [PubMed] [Google Scholar]
- Soler N. G., Nicholson H. Diabetes and thyroid disease during pregnancy. Obstet Gynecol. 1979 Sep;54(3):318–321. [PubMed] [Google Scholar]
