Skip to main content
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 1982 Feb;58(676):110–111. doi: 10.1136/pgmj.58.676.110

Normotensive cardiomyopathy and malignant hypertension in phaeochromocytoma

L M Shapiro, N Trethowan, S P Singh
PMCID: PMC2426317  PMID: 7100023

Abstract

A patient with two different presentations of phaeochromocytoma is described. She initially presented with normal blood pressure and heart failure following a prolonged feverish prodrome. A provisional diagnosis of myocarditis or early congestive cardiomyopathy was made and she improved with digoxin and diuretics. Eighteen months later, after a period of normotension free from heart failure, she developed malignant hypertension with recurrence of heart failure. A phaeochromocytoma was surgically removed, with return to normal of blood pressure and cardiac status. It would seem that the initial presentation of the phaeochromocytoma was a catecholamine-induced myocarditis without hypertension and this resolved with the subsequent development of malignant hypertension. The possible mechanisms responsible for this are discussed and it is concluded that phaeochromocytoma should be considered in patients who have heart failure and persistent features of myocarditis.

Full text

PDF
110

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baker G., Zeller N. H., Weitzner S., Leach J. K. Pheochromocytoma without hypertension presenting as cardiomyopathy. Am Heart J. 1972 May;83(5):688–693. doi: 10.1016/0002-8703(72)90410-3. [DOI] [PubMed] [Google Scholar]
  2. Engelman K. Phaeochromocytoma. Clin Endocrinol Metab. 1977 Nov;6(3):769–797. doi: 10.1016/s0300-595x(77)80079-0. [DOI] [PubMed] [Google Scholar]
  3. Shapiro L. M., Mackinnon J., Beevers D. G. Echocardiographic features of malignant hypertension. Br Heart J. 1981 Oct;46(4):374–379. doi: 10.1136/hrt.46.4.374. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Swedberg K., Hjalmarson A., Waagstein F., Wallentin I. Beneficial effects of long-term beta-blockade in congestive cardiomyopathy. Br Heart J. 1980 Aug;44(2):117–133. doi: 10.1136/hrt.44.2.117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Van Vliet P. D., Burchell H. B., Titus J. L. Focal myocarditis associated with pheochromocytoma. N Engl J Med. 1966 May 19;274(20):1102–1108. doi: 10.1056/NEJM196605192742002. [DOI] [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES