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. 1982 Apr;58(678):233–234. doi: 10.1136/pgmj.58.678.233

Warfarin-induced vasculitis: A dose-related phenomenon in susceptible individuals?

A J Howitt, A J Williams, Craig Skinner
PMCID: PMC2426397  PMID: 6213948

Abstract

A case of warfarin-induced skin vasculitis in a 52-year-old female is reported. Bilateral breast involvement occurred but without progression to necrosis as in previously described cases. The pathogenesis is discussed and prescribing recommendations made in an attempt to avoid the complication in susceptible individuals.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Davis C. E., Jr, Wiley W. B., Faulconer R. J. Necrosis of the female breast complicating oral anticoagulant treatment. Ann Surg. 1972 May;175(5):647–656. doi: 10.1097/00000658-197205000-00004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Fourrier A., Combemale B., Mouton Y., Wache F., Taccoen P., Beaucaire G. La nécrose mammaire au cours du traitement par les anti-vitamine K. A propos de 2 nouvelles observations. Lille Med. 1979 Aug-Sep;24(7):523–526. [PubMed] [Google Scholar]
  3. NALBANDIAN R. M., MADER I. J., BARRETT J. L., PEARCE J. F., RUPP E. C. PETECHIAE, ECCHYMOSES, AND NECROSIS OF SKIN INDUCED BY COUMARIN CONGENERS: RARE, OCCASIONALLY LETHAL COMPLICATION OF ANTICOAGULANT THERAPY. JAMA. 1965 May 17;192:603–608. doi: 10.1001/jama.1965.03080200021006. [DOI] [PubMed] [Google Scholar]
  4. Nudelman H. L., Kempson R. L. Necrosis of the breast: a rare complication of anticoagulant therapy. Am J Surg. 1966 May;111(5):728–733. doi: 10.1016/0002-9610(66)90051-1. [DOI] [PubMed] [Google Scholar]
  5. Stavorovsky M., Lichtenstein D., Nissim F. Skin petechiae and ecchymoses (vasculitis) due to anticoagulant therapy. Dermatologica. 1979;158(6):451–461. doi: 10.1159/000250797. [DOI] [PubMed] [Google Scholar]

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