Skip to main content
NCBI home page
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 1982 Nov;58(685):726–728. doi: 10.1136/pgmj.58.685.726

Pseudomembranous colitis following cephradine prophylaxis.

M Sankarankutty, D McGeorge, C S Galasko
PMCID: PMC2426554  PMID: 7170277

Abstract

Two patients on antibiotic prophylaxis with cephradine after orthopaedic implant surgery developed pseudomembranous colitis. Routine administration of antibiotics after such surgery is the policy at many centres. Development of diarrhoea in these patients should be viewed seriously lest this condition is overlooked. Despite recent advances, pseudomembranous colitis can still have a fatal outcome.

Full text

PDF
726

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bartlett J. G., Chang T. W., Gurwith M., Gorbach S. L., Onderdonk A. B. Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia. N Engl J Med. 1978 Mar 9;298(10):531–534. doi: 10.1056/NEJM197803092981003. [DOI] [PubMed] [Google Scholar]
  2. Beavis J. P., Parsons R. L., Salfield J. Colitis and diarrhoea: a problem with antibiotic therapy. Br J Surg. 1976 Apr;63(4):299–304. doi: 10.1002/bjs.1800630412. [DOI] [PubMed] [Google Scholar]
  3. Fitzgerald R. H., Jr, Nolan D. R., Ilstrup D. M., Van Scoy R. E., Washington J. A., 2nd, Coventry M. B. Deep wound sepsis following total hip arthroplasty. J Bone Joint Surg Am. 1977 Oct;59(7):847–855. [PubMed] [Google Scholar]
  4. George R. H., Symonds J. M., Dimock F., Brown J. D., Arabi Y., Shinagawa N., Keighley M. R., Alexander-Williams J., Burdon D. W. Identification of Clostridium difficile as a cause of pseudomembranous colitis. Br Med J. 1978 Mar 18;1(6114):695–695. doi: 10.1136/bmj.1.6114.695. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Hawker P. C., Hine K. R., Burdon D. W., Thompson H., Keighley M. R. Fatal pseudomembranous colitis despite eradication of Clostridium difficile. Br Med J (Clin Res Ed) 1981 Jan 10;282(6258):109–110. doi: 10.1136/bmj.282.6258.109. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Hutcheon D. F., Milligan F. D., Yardley J. H., Hendrix T. R. Cephalosporin-associated pseudomembranous colitis. Am J Dig Dis. 1978 Apr;23(4):321–326. doi: 10.1007/BF01072414. [DOI] [PubMed] [Google Scholar]
  7. Keating J. P., Frank A. L., Barton L. L., Tedesco F. J. Pseudomembranous colitis associated with ampicillin therapy. Am J Dis Child. 1974 Sep;128(3):369–370. doi: 10.1001/archpedi.1974.02110280099014. [DOI] [PubMed] [Google Scholar]
  8. Newman R. J., McCollum C. M. Pseudomembranous colitis due to cephradine. Br J Clin Pract. 1979 Jan;33(1):32–33. [PubMed] [Google Scholar]
  9. Ritchie P. H., Pennington C. R. Pseudomembranous colitis. Scott Med J. 1980 Oct;25(4):278–280. doi: 10.1177/003693308002500406. [DOI] [PubMed] [Google Scholar]
  10. Scott A. J., Nicholson G. I., Kerr A. R. Lincomycin as a cause of pseudomembranous colitis. Lancet. 1973 Dec 1;2(7840):1232–1234. doi: 10.1016/s0140-6736(73)90973-2. [DOI] [PubMed] [Google Scholar]
  11. Tan J., Bayne L. H., McLeod P. J. Pseudomembranous colitis. A fatal case following prophylactic cephaloridine therapy. JAMA. 1979 Aug 24;242(8):749–750. doi: 10.1001/jama.242.8.749. [DOI] [PubMed] [Google Scholar]
  12. Tedesco F. J., Barton R. W., Alpers D. H. Clindamycin-associated colitis. A prospective study. Ann Intern Med. 1974 Oct;81(4):429–433. doi: 10.7326/0003-4819-81-4-429. [DOI] [PubMed] [Google Scholar]
  13. Tedesco F., Markham R., Gurwith M., Christie D., Bartlett J. G. Oral vancomycin for antibiotic-associated pseudomembranous colitis. Lancet. 1978 Jul 29;2(8083):226–228. doi: 10.1016/s0140-6736(78)91741-5. [DOI] [PubMed] [Google Scholar]
  14. Tures J. F., Townsend W. F., Rose H. D. Cephalosporin-associated pseudomembranous colitis. JAMA. 1976 Aug 23;236(8):948–949. [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES