Abstract
Relatively few studies have been made of the exposure of workers to pesticides. Of these, approximately half involved chlorinated hydrocarbon insecticides, and most involved agricultural applications. Some important matters, especially indoor spraying—e.g., for malaria control—have been investigated experimentally with DDT only. Fortunately, information on exposure during agricultural use—which is of considerable interest in itself—can serve as a rough guide in connexion with the exposures associated with vector-control activities. This paper reviews the different methods of measuring exposure and the significance of some of the results that have been obtained.
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Selected References
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- ARTERBERRY J. D., DURHAM W. F., ELLIOTT J. W., WOLFE H. R. Exposure to parathion. Measurement by blood cholinesterase level and urinary p-nitrophenol excretion. Arch Environ Health. 1961 Oct;3:476–485. doi: 10.1080/00039896.1961.10663054. [DOI] [PubMed] [Google Scholar]
- Antommaria P., Corn M., DeMaio L. Airborne particulates in Pittsburgh: association with p, p -DDT. Science. 1965 Dec 10;150(3702):1476–1477. doi: 10.1126/science.150.3702.1476. [DOI] [PubMed] [Google Scholar]
- BATCHELOR G. S., WALKER K. C. Health hazards involved in use of parathion in fruit orchards of North Central Washington. AMA Arch Ind Health. 1954 Dec;10(6):522–529. [PubMed] [Google Scholar]
- BEST E. M., Jr, MURRAY B. L. Observations on workers exposed to Sevin insecticide: a preliminary report. J Occup Med. 1962 Oct;4:507–517. [PubMed] [Google Scholar]
- CAPLAN P. E., CULVER D., THIELEN W. C. Human exposures in populated areas during airplane application of malathion. AMA Arch Ind Health. 1956 Oct;14(4):326–332. [PubMed] [Google Scholar]
- DAWSON J. A., HEATH D. F., ROSE J. A., THAIN E. M., WARD J. B. THE EXCRETION BY HUMANS OF THE PHENOL DERIVED IN VIVO FROM 2-ISOPROPOXYPHENYL N-METHYLCARBAMATE. Bull World Health Organ. 1964;30:127–134. [PMC free article] [PubMed] [Google Scholar]
- DURHAM W. F., WOLFE H. R. AN ADDITIONAL NOTE REGARDING MEASUREMENT OF THE EXPOSURE OF WORKERS TO PESTICIDES. Bull World Health Organ. 1963;29:279–281. [PMC free article] [PubMed] [Google Scholar]
- DURHAM W. F., WOLFE H. R. Measurement of the exposure of workers to pesticides. Bull World Health Organ. 1962;26:75–91. [PMC free article] [PubMed] [Google Scholar]
- Gaines T. B. Acute toxicity of pesticides. Toxicol Appl Pharmacol. 1969 May;14(3):515–534. doi: 10.1016/0041-008x(69)90013-1. [DOI] [PubMed] [Google Scholar]
- Gaines T. B., Hayes W. J., Jr, Linder R. E. Liver metabolism of anticholinesterase compounds in live rats: relation to toxicity. Nature. 1966 Jan 1;209(5018):88–89. doi: 10.1038/209088a0. [DOI] [PubMed] [Google Scholar]
- HAYES W. J., Jr, MATTSON A. M., SHORT J. G., WITTER R. F. Safety of malathion dusting powder for louse control. Bull World Health Organ. 1960;22:503–514. [PMC free article] [PubMed] [Google Scholar]
- JEGIER Z. EXPOSURE TO GUTHION DURING SPRAYING AND FORMULATING. Arch Environ Health. 1964 Apr;8:565–569. doi: 10.1080/00039896.1964.10663718. [DOI] [PubMed] [Google Scholar]
- JEGIER Z. HEALTH HAZARDS IN INSECTICIDE SPRAYING OF CROPS. Arch Environ Health. 1964 May;8:670–674. doi: 10.1080/00039896.1964.10663738. [DOI] [PubMed] [Google Scholar]
- Laws E. R., Jr, Morales F. R., Hayes J., Jr, Joseph C. R. Toxicology of Abate in volunteers. Arch Environ Health. 1967 Feb;14(2):289–291. doi: 10.1080/00039896.1967.10664733. [DOI] [PubMed] [Google Scholar]
- MILBY T. H., OTTOBONI F., MITCHELL H. W. PARATHION RESIDUE POISONING AMONG ORCHARD WORKERS. JAMA. 1964 Aug 3;189:351–356. doi: 10.1001/jama.1964.03070050017004. [DOI] [PubMed] [Google Scholar]
- QUINBY G. E., LEMMON A. B. Parathion residues as a cause of poisoning in crop workers. J Am Med Assoc. 1958 Feb 15;166(7):740–746. doi: 10.1001/jama.1958.02990070026007. [DOI] [PubMed] [Google Scholar]
- QUINBY G. E., LOOMIS T. A., BROWN H. W. Oral occupational parathion poisoning treated with 2-PAM iodide (2-pyridine aldoxime methiodide). N Engl J Med. 1963 Mar 21;268:639–643. doi: 10.1056/NEJM196303212681202. [DOI] [PubMed] [Google Scholar]
- SIMPSON G. R. EXPOSURE TO ORCHARD PESTICIDES: DERMAL AND INHALATION EXPOSURES. Arch Environ Health. 1965 Jun;10:884–885. doi: 10.1080/00039896.1965.10664113. [DOI] [PubMed] [Google Scholar]
- Simpson G. R., Beck A. Exposure to parathion. Dermal and inhalation exposure to parathion while spraying tomato bushes with a Knap-Sack Mister. Arch Environ Health. 1965 Dec;11(6):784–786. doi: 10.1080/00039896.1965.10664301. [DOI] [PubMed] [Google Scholar]
- Stein W. J., Miller S., Fetzer L. E., Jr Studies with dichlorvos residual fumigant as a malaria eradication technique in Haiti. 3. Toxicological studies. Am J Trop Med Hyg. 1966 Sep;15(5):672–675. doi: 10.4269/ajtmh.1966.15.672. [DOI] [PubMed] [Google Scholar]
- Tabor E. C. Contamination of urban air through the use of insecticides. Trans N Y Acad Sci. 1966 Mar;28(5):569–578. doi: 10.1111/j.2164-0947.1966.tb02374.x. [DOI] [PubMed] [Google Scholar]
- Vandekar M., Hedayat S., Plestina R., Ahmady G. A study of the safety of O-isopropoxyphenylmethylcarbamate in an operational field-trial in Iran. Bull World Health Organ. 1968;38(4):609–623. [PMC free article] [PubMed] [Google Scholar]
- Vandekar M., Plestina R., Wilhelm K. Toxicity of carbamates for mammals. Bull World Health Organ. 1971;44(1-3):241–249. [PMC free article] [PubMed] [Google Scholar]
- Vandekar M., Wilford K. The effect on cholinesterase activity of storage of undiluted whole blood sampled from men exposed to o-isopropoxyphenyl methylcarbamate (OMS-33). Bull World Health Organ. 1969;40(1):91–96. [PMC free article] [PubMed] [Google Scholar]
- WASSERMANN M., ILIESCU S., MANDRIC G., HORVATH P. Toxic hazards during DDT- and BHC-spraying of forests against Lymantria monacha. AMA Arch Ind Health. 1960 Jun;21:503–508. [PubMed] [Google Scholar]
- WOLFE H. R., DURHAM W. F., ARMSTRONG J. F. Health hazards of the pesticides endrin and dieldrin. Hazards in some agricultural uses in the Pacific Northwest. Arch Environ Health. 1963 Apr;6:458–464. doi: 10.1080/00039896.1963.10663426. [DOI] [PubMed] [Google Scholar]
- WOLFE H. R., WALKER K. C., ELLIOTT J. W., DURHAM W. F. Evaluation of the health hazards involved in house-spraying with DDT. Bull World Health Organ. 1959;20(1):1–14. [PMC free article] [PubMed] [Google Scholar]
- Wolfe H. R., Armstrong J. F., Durham W. F. Pesticide exposure from concentrate spraying. Arch Environ Health. 1966 Sep;13(3):340–344. doi: 10.1080/00039896.1966.10664567. [DOI] [PubMed] [Google Scholar]
- Wolfe H. R., Durham W. F., Armstrong J. F. Exposure of workers to pesticides. Arch Environ Health. 1967 Apr;14(4):622–633. doi: 10.1080/00039896.1967.10664801. [DOI] [PubMed] [Google Scholar]
- Wolfe H. R., Durham W. F., Armstrong J. F. Urinary excretion of insecticide metabolites. Excretion of para-nitrophenol and DDA as indicators of exposure to parathion. Arch Environ Health. 1970 Dec;21(6):711–716. doi: 10.1080/00039896.1970.10667324. [DOI] [PubMed] [Google Scholar]
- Wright J. W., Fritz R. F., Hocking K. S., Babione R., Gratz N. G., Pal R., Stiles A. R., Vandekar M. Ortho-isopropoxphenyl methylcarbamate (OMS-33) as a residual spray for control of anopheline mosquitos. With special reference to its evaluation in the WHO programme for evaluating and testing new insecticides. Bull World Health Organ. 1969;40(1):67–90. [PMC free article] [PubMed] [Google Scholar]
