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. Author manuscript; available in PMC: 2008 Jun 13.
Published in final edited form as: Neuroreport. 2008 Feb 12;19(3):327–331. doi: 10.1097/WNR.0b013e3282f50c7b

Fig. 3.

Fig. 3

Summary of time course differences in MMP-2 and MMP-9 expression in the olfactory bulbs of P2 and MMP-9 KO mice following olfactory nerve transection injury. The MMP-9 data (filled circles) is from NeuroReport 2006; 17:1787−1791. The average MMP/ CPA ratio from four separate time course experiments were calculated and plotted as a percent of the maximum value. In P2 mice, MMP-9 peaked very rapidly (hours) after injury and remained elevated during olfactory neuron regeneration The MMP-2 expression data for both the P2 mice (filled diamonds) and MMP-9 KO mice (open squares) show nearly identical changes in the time course of expression following injury. MMP-2 levels peaked later than MMP-9, at day 7 and returned rapidly to the lower levels observed immediately following injury. KO, Knockout; MMP, matrix metaloproteinases.