Skip to main content
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 1979 Aug;55(646):573–574. doi: 10.1136/pgmj.55.646.573

Ectopic ACTH syndrome from bronchogenic carcinoma in association with chronic lymphocytic leukaemia.

J C Forfar
PMCID: PMC2428088  PMID: 229476

Abstract

A patient under treatment for chronic lymphocytic leukaemia developed lobar pneumonia after 8 months. When antileukaemic therapy was discontinued, features of an ectopic ACTH syndrome developed, secondary to bronchogenic carcinoma. Exogenous steroid therapy for leukaemia seemed to suppress the clinical manifestations of the ectopic ACTH syndrome while subsequent endogenous steroid production controlled the peripheral lymphocyte count.

Full text

PDF
573

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Azzopardi J. G., Freeman E., Poole G. Endocrine and metabolic disordes in bronchial carcinoma. Br Med J. 1970 Nov 28;4(5734):528–530. doi: 10.1136/bmj.4.5734.528. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Gilkes J. J., Rees L. H., Besser G. M. Plasma immunoreactive corticotrophin and lipotrophin in Cushing's syndrome and Addison's disease. Br Med J. 1977 Apr 16;1(6067):996–998. doi: 10.1136/bmj.1.6067.996. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Rees L. H., Ratcliffe J. G. Ectopic hormone production by non-endocrine tumours. Clin Endocrinol (Oxf) 1974 Jul;3(3):263–299. doi: 10.1111/j.1365-2265.1974.tb01801.x. [DOI] [PubMed] [Google Scholar]
  4. Ross E. J. Cancer and the adrenal cortex. Proc R Soc Med. 1966 Apr;59(4):335–338. doi: 10.1177/003591576605900411. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Sweet D. L., Jr, Golomb H. M., Ultmann J. E. The clinical features of chronic lymphocytic leukaemia. Clin Haematol. 1977 Feb;6(1):185–202. [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES