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. 1987 Feb;63(736):91–94. doi: 10.1136/pgmj.63.736.91

Reduced plasma high-density lipoprotein and increased platelet activity in arterial versus venous blood.

M Aviram 1, A Viener 1, J G Brook 1
PMCID: PMC2428243  PMID: 3671249

Abstract

Plasma lipid and lipoprotein pattern and platelet activity were studied in blood samples derived from veins and arteries of 10 healthy male subjects. A significant reduction in plasma high-density lipoprotein (HDL) cholesterol, triglyceride and protein levels, as well as in plasma apolipoprotein A-I, was found when lipoproteins were derived from arterial blood in comparison to venous blood. All other lipoproteins were not significantly changed. Platelet activity measured as plasma beta-thromboglobulin levels and as collagen-induced platelet aggregation and 14C-serotonin release in platelet-rich plasma was markedly elevated when platelets were derived from arterial blood. Since reduced plasma HDL concentration and platelet activation are known risk factors for atherosclerosis, our study may suggest a further explanation for the presence of atherosclerotic lesions in arteries but not in veins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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