Abstract
We report a case of chronic ulcerative colitis complicated by clinical evidence of disseminated intravascular coagulation and pathological evidence of intestinal ischaemia secondary to venular and capillary fibrin thrombi. This may well represent an example of univisceral Shwartzman reaction occurring in a sensitized target organ.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brandt L. J., Gomery P., Mitsudo S. M., Chandler P., Boley S. J. Disseminated intravascular coagulation in nonocclusive mesenteric ischemia: the lack of specificity of fibrin thrombi in intestinal infarction. Gastroenterology. 1976 Dec;71(6):954–957. [PubMed] [Google Scholar]
- Endo K., Miura N., Sato T., Unoura A., Okata T., Watanabe H., Hirayama T., Kanno H., Mori K. [Two cases of ulcerative colitis complicated with disseminated intravascular coagulation]. Nihon Shokakibyo Gakkai Zasshi. 1982 Sep;79(9):1778–1782. [PubMed] [Google Scholar]
- Knot E. A., ten Cate J. W., Bruin T., Iburg A. H., Tytgat G. N. Antithrombin III metabolism in two colitis patients with acquired antithrombin III deficiency. Gastroenterology. 1985 Aug;89(2):421–425. doi: 10.1016/0016-5085(85)90346-4. [DOI] [PubMed] [Google Scholar]
- Kondo M., Yoshikawa T., Takemura S., Yokoe N., Kawai K., Masuda M. Hemorrhagic necrosis of the intestinal mucosa associated with disseminated intravascular coagulation. Digestion. 1978;17(1):38–45. doi: 10.1159/000198092. [DOI] [PubMed] [Google Scholar]
- Lake A. M., Stauffer J. Q., Stuart M. J. Hemostatic alterations in inflammatory bowel disease: response to therapy. Am J Dig Dis. 1978 Oct;23(10):897–902. doi: 10.1007/BF01072463. [DOI] [PubMed] [Google Scholar]
- Lo D. Klebsiella septicaemia, disseminated intravascular coagulation and ulcerative colitis in an Australian Aboriginal. Med J Aust. 1971 Jun 12;1(24):1279–1280. doi: 10.5694/j.1326-5377.1971.tb92392.x. [DOI] [PubMed] [Google Scholar]
- Mant M. J., King E. G. Severe, acute disseminated intravascular coagulation. A reappraisal of its pathophysiology, clinical significance and therapy based on 47 patients. Am J Med. 1979 Oct;67(4):557–563. doi: 10.1016/0002-9343(79)90225-0. [DOI] [PubMed] [Google Scholar]
- Margaretten W., McKay D. G. Thrombotic ulcerations of the gastrointestinal tract. Arch Intern Med. 1971 Feb;127(2):250–253. [PubMed] [Google Scholar]
- Mason D. Y., Heenan P. J., Whitehead R. Disseminated intravascular thrombosis as the cause of ischaemic enterocolitis. Med J Aust. 1976 Mar 27;1(13):440–442. [PubMed] [Google Scholar]
- McGovern V. J., Goulston S. J. Ischaemic enterocolitis. Gut. 1965 Jun;6(3):213–220. doi: 10.1136/gut.6.3.213. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mori W. The Shwartzman reaction: a review including clinical manifestations and proposal for a univisceral or single organ third type. Histopathology. 1981 Mar;5(2):113–126. doi: 10.1111/j.1365-2559.1981.tb01772.x. [DOI] [PubMed] [Google Scholar]
- Robboy S. J., Major M. C., Colman R. W., Minna J. D. Pathology of disseminated intravascular coagulation (DIC). Analysis of 26 cases. Hum Pathol. 1972 Sep;3(3):327–343. doi: 10.1016/s0046-8177(72)80034-0. [DOI] [PubMed] [Google Scholar]
- Shimamura K., Oka K., Nakazawa M., Kojima M. Distribution patterns of microthrombi in disseminated intravascular coagulation. Arch Pathol Lab Med. 1983 Oct;107(10):543–547. [PubMed] [Google Scholar]
- Whitehead R. Ischaemic enterocolitis: an expression of the intravascular coagulation syndrome. Gut. 1971 Nov;12(11):912–917. doi: 10.1136/gut.12.11.912. [DOI] [PMC free article] [PubMed] [Google Scholar]