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. 1987 May;63(739):393–394. doi: 10.1136/pgmj.63.739.393

Amiodarone-induced pulmonary toxicity mimicking metastatic lung disease.

P Patel 1, D Honeybourne 1, R D Watson 1
PMCID: PMC2428447  PMID: 3671275

Abstract

A 65 year old man developed atrial arrhythmias secondary to a congestive cardiomyopathy which were resistant to quinidine and disopyramide. Amiodarone controlled the paroxysmal atrial tachycardia but 4 months after starting the drug he developed increasing dyspnoea and radiological changes highly suggestive of metastatic lung disease. Lung biopsy showed change of drug-induced pneumonitis and 4 months after stopping amiodarone his symptoms resolved and the chest X-ray had cleared. Amiodarone may cause pulmonary toxicity mimicking metastatic lung disease.

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Selected References

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