Abstract
Simultaneous production of penicillic acid and patulin by an atypical strain of Penicillium roqueforti isolated from cheddar cheese is reported. Mycotoxin production was confirmed by thin-layer and gas-liquid chromatography and by ultraviolet, infrared, and mass spectral analyses. Culture extracts were toxic to Bacillus megaterium and chicken embryos. Commercial strains of P. roqueoforti used in production of blue-veined cheeses were shown not to produce penicillic acid and patulin.
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- Ciegler A., Beckwith A. C., Jackson L. K. Teratogenicity of patulin and patulin adducts formed with cysteine. Appl Environ Microbiol. 1976 May;31(5):664–667. doi: 10.1128/aem.31.5.664-667.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ciegler A., Mintzlaff H. J., Weisleder D., Leistner L. Potential production and detoxification of penicillic acid in mold-fermented sausage (salami). Appl Microbiol. 1972 Jul;24(1):114–119. doi: 10.1128/am.24.1.114-119.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DICKENS F., JONES H. E. Carcinogenic activity of a series of reactive lactones and related substances. Br J Cancer. 1961 Mar;15:85–100. doi: 10.1038/bjc.1961.10. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Norstadt F. A., McCalla T. M. Patulin production by Penicillium urticae Bainier in batch culture. Appl Microbiol. 1969 Feb;17(2):193–196. doi: 10.1128/am.17.2.193-196.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Orth R. PR-Toxinbildung bei Penicillium roqueforti-Stämmen. Z Lebensm Unters Forsch. 1976 Feb 27;160(2):131–136. doi: 10.1007/BF01259958. [DOI] [PubMed] [Google Scholar]
- Pero R. W., Harvan D., Owens R. G., Snow J. P. A gas chromatographic method for the mycotoxin penicillic acid. J Chromatogr. 1972 Mar 1;65(3):501–506. doi: 10.1016/s0021-9673(00)84996-1. [DOI] [PubMed] [Google Scholar]
- Pero R. W., Harvan D. Stimultaneous detection of metabolites from several toxigenc fungi. J Chromatogr. 1973 Jun;80(2):255–258. doi: 10.1016/s0021-9673(01)85339-5. [DOI] [PubMed] [Google Scholar]
- Scott P. M., Kennedy P. C. Analysis of blue cheese for roquefortine and other alkaloids from Penicillium roqueforti. J Agric Food Chem. 1976 Jul-Aug;24(4):865–868. doi: 10.1021/jf60206a028. [DOI] [PubMed] [Google Scholar]
- Stott W. T., Bullerman L. B. Influence of carbohydrate and nitrogen source on patulin production by Penicillium patulum. Appl Microbiol. 1975 Nov;30(5):850–854. doi: 10.1128/am.30.5.850-854.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Van Eijk G. W. Isolation and identification of orsellinic acid and penicillic acid produced by Penicillium fennelliae Stolk. Antonie Van Leeuwenhoek. 1969;35(4):497–504. doi: 10.1007/BF02219167. [DOI] [PubMed] [Google Scholar]
- Wei R. D., Still P. E., Smalley E. B., Schnoes H. K., Strong F. M. Isolation and partial characterization of a mycotoxin from Penicillium roqueforti. Appl Microbiol. 1973 Jan;25(1):111–114. doi: 10.1128/am.25.1.111-114.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]