Skip to main content
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 1987 Dec;63(746):1089–1090. doi: 10.1136/pgmj.63.746.1089

Paroxysmal kinesigenic choreoathetosis in hyperthyroidism.

M E Drake Jr 1
PMCID: PMC2428567  PMID: 3451237

Abstract

Paroxysmal kinesigenic choreoathetosis is an unusual movement disorder often triggered by attempts to use the limbs, and has sometimes been associated with diffuse or focal brain injury. We report its occurrence in hyperthyroidism, with which choreoathetosis has rarely been described in the past without known cause. Choreoathetosis has also occurred with other metabolic and toxic disorders, and the mechanism is uncertain. The development of involuntary movements activated by limb motion during hyperthyroidism suggests an influence by thyroid hormone or metabolic state on motor neurone excitability or motor system organization.

Full text

PDF
1089

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Drake M. E., Jr, Jackson R. D., Miller C. A. Paroxysmal choreoathetosis after head injury. J Neurol Neurosurg Psychiatry. 1986 Jul;49(7):837–838. doi: 10.1136/jnnp.49.7.837. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Fidler S. M., O'Rourke R. A., Buchsbaum H. W. Choreoathetosis as a manifestation of thyrotoxicosis. Neurology. 1971 Jan;21(1):55–57. doi: 10.1212/wnl.21.1.55. [DOI] [PubMed] [Google Scholar]
  3. Kertesz A. Paroxysmal kinesigenic choreoathetosis. An entity within the paroxysmal choreoathetosis syndrome. Description of 10 cases, including 1 autopsied. Neurology. 1967 Jul;17(7):680–690. doi: 10.1212/wnl.17.7.680. [DOI] [PubMed] [Google Scholar]
  4. Lance J. W. Familial paroxysmal dystonic choreoathetosis and its differentiation from related syndromes. Ann Neurol. 1977 Oct;2(4):285–293. doi: 10.1002/ana.410020405. [DOI] [PubMed] [Google Scholar]
  5. ROSEN J. A. PAROXYSMAL CHOREOATHETOSIS. ASSOCIATED WITH PERINATAL HYPOXIC ENCEPHALOPATHY. Arch Neurol. 1964 Oct;11:385–387. doi: 10.1001/archneur.1964.00460220047007. [DOI] [PubMed] [Google Scholar]
  6. Sunohara N., Mukoyama M., Mano Y., Satoyoshi E. Action-induced rhythmic dystonia: an autopsy case. Neurology. 1984 Mar;34(3):321–327. doi: 10.1212/wnl.34.3.321. [DOI] [PubMed] [Google Scholar]
  7. Van Uitert R. L., Russakoff L. M. Hyperthyroid chorea mimicking psychiatric disease. Am J Psychiatry. 1979 Sep;136(9):1208–1210. doi: 10.1176/ajp.136.9.1208. [DOI] [PubMed] [Google Scholar]
  8. Wilson W., Jefferson J. W. Thyroid disease, behavior, and psychopharmacology. Psychosomatics. 1985 Jun;26(6):481–492. doi: 10.1016/s0033-3182(85)72829-0. [DOI] [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES