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. 1987 Dec;63(746):1061–1068. doi: 10.1136/pgmj.63.746.1061

Colony-stimulating factors in the pathogenesis and treatment of disease.

D J Williamson 1, C G Begley 1
PMCID: PMC2428601  PMID: 3330237

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Selected References

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  1. Arnaout M. A., Wang E. A., Clark S. C., Sieff C. A. Human recombinant granulocyte-macrophage colony-stimulating factor increases cell-to-cell adhesion and surface expression of adhesion-promoting surface glycoproteins on mature granulocytes. J Clin Invest. 1986 Aug;78(2):597–601. doi: 10.1172/JCI112615. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Asano S., Urabe A., Okabe T., Sato N., Kondo Y. Demonstration of granulopoietic factor(s) in the plasma of nude mice transplanted with a human lung cancer and in the tumor tissue. Blood. 1977 May;49(5):845–852. [PubMed] [Google Scholar]
  3. Azuma C., Tanabe T., Konishi M., Kinashi T., Noma T., Matsuda F., Yaoita Y., Takatsu K., Hammarström L., Smith C. I. Cloning of cDNA for human T-cell replacing factor (interleukin-5) and comparison with the murine homologue. Nucleic Acids Res. 1986 Nov 25;14(22):9149–9158. doi: 10.1093/nar/14.22.9149. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Barlow D. P., Bućan M., Lehrach H., Hogan B. L., Gough N. M. Close genetic and physical linkage between the murine haemopoietic growth factor genes GM-CSF and Multi-CSF (IL3). EMBO J. 1987 Mar;6(3):617–623. doi: 10.1002/j.1460-2075.1987.tb04799.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Basten A., Beeson P. B. Mechanism of eosinophilia. II. Role of the lymphocyte. J Exp Med. 1970 Jun 1;131(6):1288–1305. doi: 10.1084/jem.131.6.1288. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Begley C. G., Lopez A. F., Nicola N. A., Warren D. J., Vadas M. A., Sanderson C. J., Metcalf D. Purified colony-stimulating factors enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive microassay for colony-stimulating factors. Blood. 1986 Jul;68(1):162–166. [PubMed] [Google Scholar]
  7. Begley C. G., Metcalf D., Nicola N. A. Purified colony stimulating factors (G-CSF and GM-CSF) induce differentiation in human HL60 leukemic cells with suppression of clonogenicity. Int J Cancer. 1987 Jan 15;39(1):99–105. doi: 10.1002/ijc.2910390118. [DOI] [PubMed] [Google Scholar]
  8. Beutler B., Greenwald D., Hulmes J. D., Chang M., Pan Y. C., Mathison J., Ulevitch R., Cerami A. Identity of tumour necrosis factor and the macrophage-secreted factor cachectin. Nature. 1985 Aug 8;316(6028):552–554. doi: 10.1038/316552a0. [DOI] [PubMed] [Google Scholar]
  9. Brennan J. K., DiPersio J. F., Abboud C. N., Lichtman M. A. The exceptional responsiveness of certain human myeloid leukemia cells to colony-stimulating activity. Blood. 1979 Dec;54(6):1230–1239. [PubMed] [Google Scholar]
  10. Broudy V. C., Kaushansky K., Segal G. M., Harlan J. M., Adamson J. W. Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor. Proc Natl Acad Sci U S A. 1986 Oct;83(19):7467–7471. doi: 10.1073/pnas.83.19.7467. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Cantrell M. A., Anderson D., Cerretti D. P., Price V., McKereghan K., Tushinski R. J., Mochizuki D. Y., Larsen A., Grabstein K., Gillis S. Cloning, sequence, and expression of a human granulocyte/macrophage colony-stimulating factor. Proc Natl Acad Sci U S A. 1985 Sep;82(18):6250–6254. doi: 10.1073/pnas.82.18.6250. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Chan J. Y., Slamon D. J., Nimer S. D., Golde D. W., Gasson J. C. Regulation of expression of human granulocyte/macrophage colony-stimulating factor. Proc Natl Acad Sci U S A. 1986 Nov;83(22):8669–8673. doi: 10.1073/pnas.83.22.8669. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Clark-Lewis I., Aebersold R., Ziltener H., Schrader J. W., Hood L. E., Kent S. B. Automated chemical synthesis of a protein growth factor for hemopoietic cells, interleukin-3. Science. 1986 Jan 10;231(4734):134–139. doi: 10.1126/science.3079915. [DOI] [PubMed] [Google Scholar]
  14. David J. R., Vadas M. A., Butterworth A. E., de Brito P. A., Carvalho E. M., David R. A., Bina J. C., Andrade Z. A. Enhanced helminthotoxic capacity of eosinophils from patients with eosinophilia. N Engl J Med. 1980 Nov 13;303(20):1147–1152. doi: 10.1056/NEJM198011133032004. [DOI] [PubMed] [Google Scholar]
  15. Degliantoni G., Murphy M., Kobayashi M., Francis M. K., Perussia B., Trinchieri G. Natural killer (NK) cell-derived hematopoietic colony-inhibiting activity and NK cytotoxic factor. Relationship with tumor necrosis factor and synergism with immune interferon. J Exp Med. 1985 Nov 1;162(5):1512–1530. doi: 10.1084/jem.162.5.1512. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Emery P., Williamson D. J., Mackay I. R. Role of cytokines in rheumatological inflammation. Concepts Immunopathol. 1987;4:171–199. [PubMed] [Google Scholar]
  17. Fleischmann J., Golde D. W., Weisbart R. H., Gasson J. C. Granulocyte-macrophage colony-stimulating factor enhances phagocytosis of bacteria by human neutrophils. Blood. 1986 Sep;68(3):708–711. [PubMed] [Google Scholar]
  18. Francis G. E., Berney J. J., Chipping P. M., Hoffbrand A. V. Stimulation of human haemopoietic cells by colony stimulating factors: sensitivity of leukaemia cells. Br J Haematol. 1979 Apr;41(4):545–562. doi: 10.1111/j.1365-2141.1979.tb05892.x. [DOI] [PubMed] [Google Scholar]
  19. Gabrilove J. L., Welte K., Harris P., Platzer E., Lu L., Levi E., Mertelsmann R., Moore M. A. Pluripoietin alpha: a second human hematopoietic colony-stimulating factor produced by the human bladder carcinoma cell line 5637. Proc Natl Acad Sci U S A. 1986 Apr;83(8):2478–2482. doi: 10.1073/pnas.83.8.2478. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Gasson J. C., Weisbart R. H., Kaufman S. E., Clark S. C., Hewick R. M., Wong G. G., Golde D. W. Purified human granulocyte-macrophage colony-stimulating factor: direct action on neutrophils. Science. 1984 Dec 14;226(4680):1339–1342. doi: 10.1126/science.6390681. [DOI] [PubMed] [Google Scholar]
  21. Gough N. M., Gough J., Metcalf D., Kelso A., Grail D., Nicola N. A., Burgess A. W., Dunn A. R. Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte-macrophage colony stimulating factor. 1984 Jun 28-Jul 4Nature. 309(5971):763–767. doi: 10.1038/309763a0. [DOI] [PubMed] [Google Scholar]
  22. Greenberg P. L., Mara B., Heller P. Marrow adherent cell colony-stimulating activity production in acute myeloid leukemia. Blood. 1978 Aug;52(2):362–378. [PubMed] [Google Scholar]
  23. Hayashi M., Okabe J., Hozumi M. Sensitization of resistant myeloid leukemia clone cells by anti-cancer drugs to factor-stimulating differentiation. Gan. 1979 Apr;70(2):235–238. [PubMed] [Google Scholar]
  24. Horwich A. Oncogenes and human cancer. Br J Hosp Med. 1984 Nov;32(5):262–266. [PubMed] [Google Scholar]
  25. Huebner K., Isobe M., Croce C. M., Golde D. W., Kaufman S. E., Gasson J. C. The human gene encoding GM-CSF is at 5q21-q32, the chromosome region deleted in the 5q- anomaly. Science. 1985 Dec 13;230(4731):1282–1285. doi: 10.1126/science.2999978. [DOI] [PubMed] [Google Scholar]
  26. Ishizaka Y., Motoyoshi K., Hatake K., Saito M., Takaku F., Miura Y. Mode of action of human urinary colony-stimulating factor. Exp Hematol. 1986 Jan;14(1):1–8. [PubMed] [Google Scholar]
  27. Johnson G. R. Factors altering the ability of multipotential hemopoietic colony-forming cells to self-generate or form progenitor cells. Leuk Res. 1983;7(5):655–666. doi: 10.1016/0145-2126(83)90136-4. [DOI] [PubMed] [Google Scholar]
  28. Kaneko S., Motomura S., Ibayashi H. Differentiation of human bone marrow-derived fibroblastoid colony forming cells (CFU-F) and their roles in haemopoiesis in vitro. Br J Haematol. 1982 Jun;51(2):217–225. doi: 10.1111/j.1365-2141.1982.tb02774.x. [DOI] [PubMed] [Google Scholar]
  29. Kawasaki E. S., Ladner M. B., Wang A. M., Van Arsdell J., Warren M. K., Coyne M. Y., Schweickart V. L., Lee M. T., Wilson K. J., Boosman A. Molecular cloning of a complementary DNA encoding human macrophage-specific colony-stimulating factor (CSF-1). Science. 1985 Oct 18;230(4723):291–296. doi: 10.1126/science.2996129. [DOI] [PubMed] [Google Scholar]
  30. Kelso A., Metcalf D. Clonal heterogeneity in colony stimulating factor production by murine T lymphocytes. J Cell Physiol. 1985 Apr;123(1):101–110. doi: 10.1002/jcp.1041230115. [DOI] [PubMed] [Google Scholar]
  31. Klebanoff S. J., Vadas M. A., Harlan J. M., Sparks L. H., Gamble J. R., Agosti J. M., Waltersdorph A. M. Stimulation of neutrophils by tumor necrosis factor. J Immunol. 1986 Jun 1;136(11):4220–4225. [PubMed] [Google Scholar]
  32. Lang R. A., Metcalf D., Gough N. M., Dunn A. R., Gonda T. J. Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity. Cell. 1985 Dec;43(2 Pt 1):531–542. doi: 10.1016/0092-8674(85)90182-5. [DOI] [PubMed] [Google Scholar]
  33. Le Beau M. M., Westbrook C. A., Diaz M. O., Larson R. A., Rowley J. D., Gasson J. C., Golde D. W., Sherr C. J. Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders. Science. 1986 Feb 28;231(4741):984–987. doi: 10.1126/science.3484837. [DOI] [PubMed] [Google Scholar]
  34. Lee F., Yokota T., Otsuka T., Gemmell L., Larson N., Luh J., Arai K., Rennick D. Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells. Proc Natl Acad Sci U S A. 1985 Jul;82(13):4360–4364. doi: 10.1073/pnas.82.13.4360. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Lopez A. F., Williamson D. J., Gamble J. R., Begley C. G., Harlan J. M., Klebanoff S. J., Waltersdorph A., Wong G., Clark S. C., Vadas M. A. Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival. J Clin Invest. 1986 Nov;78(5):1220–1228. doi: 10.1172/JCI112705. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Lord B. I., Molineux G., Testa N. G., Kelly M., Spooncer E., Dexter T. M. The kinetic response of haemopoietic precursor cells, in vivo, to highly purified, recombinant interleukin-3. Lymphokine Res. 1986 Spring;5(2):97–104. [PubMed] [Google Scholar]
  37. Lotem J., Sachs L. In vivo inhibition of the development of myeloid leukemia by injection of macrophage- and granulocyte-inducing protein. Int J Cancer. 1981 Sep 15;28(3):375–386. doi: 10.1002/ijc.2910280318. [DOI] [PubMed] [Google Scholar]
  38. Metcalf D., Begley C. G., Johnson G. R., Nicola N. A., Lopez A. F., Williamson D. J. Effects of purified bacterially synthesized murine multi-CSF (IL-3) on hematopoiesis in normal adult mice. Blood. 1986 Jul;68(1):46–57. [PubMed] [Google Scholar]
  39. Metcalf D., Begley C. G., Johnson G. R., Nicola N. A., Vadas M. A., Lopez A. F., Williamson D. J., Wong G. G., Clark S. C., Wang E. A. Biologic properties in vitro of a recombinant human granulocyte-macrophage colony-stimulating factor. Blood. 1986 Jan;67(1):37–45. [PubMed] [Google Scholar]
  40. Metcalf D. The molecular biology and functions of the granulocyte-macrophage colony-stimulating factors. Blood. 1986 Feb;67(2):257–267. [PubMed] [Google Scholar]
  41. Moore M. A., Williams N., Metcalf D. In vitro colony formation by normal and leukemic human hematopoietic cells: interaction between colony-forming and colony-stimulating cells. J Natl Cancer Inst. 1973 Mar;50(3):591–602. doi: 10.1093/jnci/50.3.591. [DOI] [PubMed] [Google Scholar]
  42. Munker R., Gasson J., Ogawa M., Koeffler H. P. Recombinant human TNF induces production of granulocyte-monocyte colony-stimulating factor. Nature. 1986 Sep 4;323(6083):79–82. doi: 10.1038/323079a0. [DOI] [PubMed] [Google Scholar]
  43. Nagao T., Yamauchi K., Komatsuda M., Noguchi K., Shimizu M., Yonekura S., Nozaki H. Inhibition of human bone marrow fibroblast colony formation by leukemic cells. Blood. 1983 Dec;62(6):1261–1265. [PubMed] [Google Scholar]
  44. Nicola N. A., Begley C. G., Metcalf D. Identification of the human analogue of a regulator that induces differentiation in murine leukaemic cells. Nature. 1985 Apr 18;314(6012):625–628. doi: 10.1038/314625a0. [DOI] [PubMed] [Google Scholar]
  45. Nicola N. A., Metcalf D. Binding of the differentiation-inducer, granulocyte-colony-stimulating factor, to responsive but not unresponsive leukemic cell lines. Proc Natl Acad Sci U S A. 1984 Jun;81(12):3765–3769. doi: 10.1073/pnas.81.12.3765. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Nienhuis A. W., Bunn H. F., Turner P. H., Gopal T. V., Nash W. G., O'Brien S. J., Sherr C. J. Expression of the human c-fms proto-oncogene in hematopoietic cells and its deletion in the 5q- syndrome. Cell. 1985 Sep;42(2):421–428. doi: 10.1016/0092-8674(85)90099-6. [DOI] [PubMed] [Google Scholar]
  47. Owhashi M., Nawa Y. Granulocyte-macrophage colony-stimulating factor produced by splenic T lymphocytes of mice infected with Schistosoma japonicum. Infect Immun. 1986 Jan;51(1):213–217. doi: 10.1128/iai.51.1.213-217.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  48. Piacibello W., Lu L., Wachter M., Rubin B., Broxmeyer H. E. Release of granulocyte-macrophage colony stimulating factors from major histocompatibility complex class II antigen-positive monocytes is enhanced by human gamma interferon. Blood. 1985 Dec;66(6):1343–1351. [PubMed] [Google Scholar]
  49. Rosenblatt M. Peptide hormone antagonists that are effective in vivo. Lessons from parathyroid hormone. N Engl J Med. 1986 Oct 16;315(16):1004–1013. doi: 10.1056/NEJM198610163151606. [DOI] [PubMed] [Google Scholar]
  50. Sachs L. Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia. Nature. 1978 Aug 10;274(5671):535–539. doi: 10.1038/274535a0. [DOI] [PubMed] [Google Scholar]
  51. Schrader J. W., Crapper R. M. Autogenous production of a hemopoietic growth factor, persisting-cell-stimulating factor, as a mechanism for transformation of bone marrow-derived cells. Proc Natl Acad Sci U S A. 1983 Nov;80(22):6892–6896. doi: 10.1073/pnas.80.22.6892. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Shapiro M. E., Kasper D. L., Zaleznik D. F., Spriggs S., Onderdonk A. B., Finberg R. W. Cellular control of abscess formation: role of T cells in the regulation of abscesses formed in response to Bacteroides fragilis. J Immunol. 1986 Jul 1;137(1):341–346. [PubMed] [Google Scholar]
  53. Shaw G., Kamen R. A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell. 1986 Aug 29;46(5):659–667. doi: 10.1016/0092-8674(86)90341-7. [DOI] [PubMed] [Google Scholar]
  54. Sherr C. J., Rettenmier C. W., Sacca R., Roussel M. F., Look A. T., Stanley E. R. The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell. 1985 Jul;41(3):665–676. doi: 10.1016/s0092-8674(85)80047-7. [DOI] [PubMed] [Google Scholar]
  55. Silberstein D. S., David J. R. Tumor necrosis factor enhances eosinophil toxicity to Schistosoma mansoni larvae. Proc Natl Acad Sci U S A. 1986 Feb;83(4):1055–1059. doi: 10.1073/pnas.83.4.1055. [DOI] [PMC free article] [PubMed] [Google Scholar]
  56. Souza L. M., Boone T. C., Gabrilove J., Lai P. H., Zsebo K. M., Murdock D. C., Chazin V. R., Bruszewski J., Lu H., Chen K. K. Recombinant human granulocyte colony-stimulating factor: effects on normal and leukemic myeloid cells. Science. 1986 Apr 4;232(4746):61–65. doi: 10.1126/science.2420009. [DOI] [PubMed] [Google Scholar]
  57. Stanley E., Metcalf D., Sobieszczuk P., Gough N. M., Dunn A. R. The structure and expression of the murine gene encoding granulocyte-macrophage colony stimulating factor: evidence for utilisation of alternative promoters. EMBO J. 1985 Oct;4(10):2569–2573. doi: 10.1002/j.1460-2075.1985.tb03972.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  58. Strath M., Sanderson C. J. Detection of eosinophil differentiation factor and its relationship to eosinophilia in Mesocestoides corti-infected mice. Exp Hematol. 1986 Jan;14(1):16–20. [PubMed] [Google Scholar]
  59. Thorne K. J., Richardson B. A., Taverne J., Williamson D. J., Vadas M. A., Butterworth A. E. A comparison of eosinophil-activating factor (EAF) with other monokines and lymphokines. Eur J Immunol. 1986 Sep;16(9):1143–1149. doi: 10.1002/eji.1830160919. [DOI] [PubMed] [Google Scholar]
  60. Tsuchiya M., Nomura H., Asano S., Kaziro Y., Nagata S. Characterization of recombinant human granulocyte-colony-stimulating factor produced in mouse cells. EMBO J. 1987 Mar;6(3):611–616. doi: 10.1002/j.1460-2075.1987.tb04798.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  61. Wahl S. M., Hunt D. A., Allen J. B., Wilder R. L., Paglia L., Hand A. R. Bacterial cell wall-induced hepatic granulomas. An in vivo model of T cell-dependent fibrosis. J Exp Med. 1986 Apr 1;163(4):884–902. doi: 10.1084/jem.163.4.884. [DOI] [PMC free article] [PubMed] [Google Scholar]
  62. Wang J. M., Colella S., Allavena P., Mantovani A. Chemotactic activity of human recombinant granulocyte-macrophage colony-stimulating factor. Immunology. 1987 Mar;60(3):439–444. [PMC free article] [PubMed] [Google Scholar]
  63. Warren M. K., Ralph P. Macrophage growth factor CSF-1 stimulates human monocyte production of interferon, tumor necrosis factor, and colony stimulating activity. J Immunol. 1986 Oct 1;137(7):2281–2285. [PubMed] [Google Scholar]
  64. Weisbart R. H., Golde D. W., Clark S. C., Wong G. G., Gasson J. C. Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator. 1985 Mar 28-Apr 3Nature. 314(6009):361–363. doi: 10.1038/314361a0. [DOI] [PubMed] [Google Scholar]
  65. Weisbart R. H., Golde D. W., Clark S. C., Wong G. G., Gasson J. C. Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator. 1985 Mar 28-Apr 3Nature. 314(6009):361–363. doi: 10.1038/314361a0. [DOI] [PubMed] [Google Scholar]
  66. Welte K., Bonilla M. A., Gillio A. P., Boone T. C., Potter G. K., Gabrilove J. L., Moore M. A., O'Reilly R. J., Souza L. M. Recombinant human granulocyte colony-stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide-treated primates. J Exp Med. 1987 Apr 1;165(4):941–948. doi: 10.1084/jem.165.4.941. [DOI] [PMC free article] [PubMed] [Google Scholar]
  67. Wheeler E. F., Rettenmier C. W., Look A. T., Sherr C. J. The v-fms oncogene induces factor independence and tumorigenicity in CSF-1 dependent macrophage cell line. 1986 Nov 27-Dec 3Nature. 324(6095):377–380. doi: 10.1038/324377a0. [DOI] [PubMed] [Google Scholar]
  68. Williamson D. J., Brown T. C. Enhancement of neutrophil-mediated phagocytosis by human granulocyte-macrophage colony-stimulating factor demonstrated using a novel mathematical model. Immunol Cell Biol. 1987 Aug;65(Pt 4):329–335. doi: 10.1038/icb.1987.37. [DOI] [PubMed] [Google Scholar]
  69. Wong G. G., Witek J. S., Temple P. A., Wilkens K. M., Leary A. C., Luxenberg D. P., Jones S. S., Brown E. L., Kay R. M., Orr E. C. Human GM-CSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins. Science. 1985 May 17;228(4701):810–815. doi: 10.1126/science.3923623. [DOI] [PubMed] [Google Scholar]
  70. Young D. C., Wagner K., Griffin J. D. Constitutive expression of the granulocyte-macrophage colony-stimulating factor gene in acute myeloblastic leukemia. J Clin Invest. 1987 Jan;79(1):100–106. doi: 10.1172/JCI112769. [DOI] [PMC free article] [PubMed] [Google Scholar]

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