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. 1988 May;64(751):389–391. doi: 10.1136/pgmj.64.751.389

Foscarnet as treatment for cytomegalovirus retinitis following bone marrow transplantation.

P S Ganly 1, C Arthur 1, J M Goldman 1, W E Schulenburg 1
PMCID: PMC2428687  PMID: 2849092

Abstract

This report describes a patient with chronic granulocytic leukaemia who developed cataracts on busulphan treatment. Following allogeneic bone marrow transplantation, he developed cytomegalovirus retinitis, which was treated successfully with trisodium phosphonoformate (foscarnet). Cytomegalovirus retinitis and its therapy, and busulphan-induced cataract are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Acheson J. F., Shah S. M., Spalton D. J., Bradbeer C., Thin R. N. Treatment of CMV retinitis in an AIDS patient. Br J Ophthalmol. 1987 Nov;71(11):810–816. doi: 10.1136/bjo.71.11.810. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Akman N., Avanoğlu Y., Soysal T. Cataract after busulphan therapy. Acta Haematol. 1986;76(4):236–236. doi: 10.1159/000206064. [DOI] [PubMed] [Google Scholar]
  3. Bach M. C., Bagwell S. P., Knapp N. P., Davis K. M., Hedstrom P. S. 9-(1,3-Dihydroxy-2-propoxymethyl)guanine for cytomegalovirus infections in patients with the acquired immunodeficiency syndrome. Ann Intern Med. 1985 Sep;103(3):381–382. doi: 10.7326/0003-4819-103-3-381. [DOI] [PubMed] [Google Scholar]
  4. Felsenstein D., D'Amico D. J., Hirsch M. S., Neumeyer D. A., Cederberg D. M., de Miranda P., Schooley R. T. Treatment of cytomegalovirus retinitis with 9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine. Ann Intern Med. 1985 Sep;103(3):377–380. doi: 10.7326/0003-4819-103-3-377. [DOI] [PubMed] [Google Scholar]
  5. Fiala M., Payne J. E., Berne T. V., Moore T. C., Henle W., Montgomerie J. Z., Chatterjee S. N., Guze L. B. Epidemiology of cytomegalovirus infection after transplantation and immunosuppression. J Infect Dis. 1975 Oct;132(4):421–433. doi: 10.1093/infdis/132.4.421. [DOI] [PubMed] [Google Scholar]
  6. Meyers J. D., Flournoy N., Thomas E. D. Cytomegalovirus infection and specific cell-mediated immunity after marrow transplant. J Infect Dis. 1980 Dec;142(6):816–824. doi: 10.1093/infdis/142.6.816. [DOI] [PubMed] [Google Scholar]
  7. Murray H. W., Knox D. L., Green W. R., Susel R. M. Cytomegalovirus retinitis in adults. A manifestation of disseminated viral infection. Am J Med. 1977 Oct;63(4):574–584. doi: 10.1016/0002-9343(77)90203-0. [DOI] [PubMed] [Google Scholar]
  8. Pepose J. S., Holland G. N., Nestor M. S., Cochran A. J., Foos R. Y. Acquired immune deficiency syndrome. Pathogenic mechanisms of ocular disease. Ophthalmology. 1985 Apr;92(4):472–484. doi: 10.1016/s0161-6420(85)34008-3. [DOI] [PubMed] [Google Scholar]
  9. Podos S. M., Canellos G. P. Lens changes in chronic granulocytic leukemia. Possible relationship to chemotherapy. Am J Ophthalmol. 1969 Sep;68(3):500–504. doi: 10.1016/0002-9394(69)90722-3. [DOI] [PubMed] [Google Scholar]
  10. Pollard R. B., Egbert P. R., Gallagher J. G., Merigan T. C. Cytomegalovirus retinitis in immunosuppressed hosts. I. Natural history and effects of treatment with adenine arabinoside. Ann Intern Med. 1980 Nov;93(5):655–664. doi: 10.7326/0003-4819-93-5-655. [DOI] [PubMed] [Google Scholar]
  11. Ravindranathan M. P., Paul V. J., Kuriakose E. T. Cataract after busulphan treatment. Br Med J. 1972 Jan 22;1(5794):218–219. doi: 10.1136/bmj.1.5794.218. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Singer D. R., Fallon T. J., Schulenburg W. E., Williams G., Cohen J. Foscarnet for cytomegalovirus retinitis. Ann Intern Med. 1985 Dec;103(6 ):962–962. doi: 10.7326/0003-4819-103-6-962_2. [DOI] [PubMed] [Google Scholar]

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