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. 1988 Mar;64(749):236–238. doi: 10.1136/pgmj.64.749.236

Failure of penicillin prophylaxis in laboratory acquired leptospirosis.

C F Gilks 1, H P Lambert 1, E S Broughton 1, C C Baker 1
PMCID: PMC2428849  PMID: 3174544

Abstract

A laboratory technician developed leptospirosis following accidental inoculation, despite prompt administration of parenteral penicillin by an accepted regimen of post-exposure prophylaxis. Another technician was similarly exposed and was given doxycycline; no illness or serological conversion followed. The implications of these cases are discussed and recommendations made for post-exposure chemoprophylaxis with doxycycline.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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