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. 1988 Aug;64(754):621–625. doi: 10.1136/pgmj.64.754.621

Glomerulonephropathy of Laurence-Moon-Biedl syndrome.

I K Cheng 1, K W Chan 1, M K Chan 1, A Kung 1, J Ma 1, C Wang 1
PMCID: PMC2428942  PMID: 3249710

Abstract

A patient with Laurence-Moon-Biedl syndrome and nephrotic range proteinuria is presented. Radiological investigation of the urinary tract revealed clubbed calyces but no evidence of obstruction or vesicoureteric reflux. Renal biopsy revealed occasional sclerotic glomeruli, extensive foot-process fusion and segmental glomerular basement membrane abnormalities with negative immunofluorescence for immunoglobulins and complement. Nephrotic proteinuria responded to steroid therapy but mild proteinuria persisted. The findings were consistent with minimal change nephropathy superimposed on the glomerular lesions of Lawrence-Moon-Biedl syndrome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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