Abstract
A patient who died in asystole less than 18 h after ingestion of 'Clovercide Extra', a combination hormonal weedkiller containing ioxynil and 4-chloro-2-methyl phenoxypropionic acid, is described. Previous reports describe coma as an early event following ingestion of these herbicides. In contrast our patient, although showing other characteristic features, including metabolic acidosis, tachycardia, pupillary constriction and pyrexia, remained conscious until the terminal event. Absence of coma does not appear to be related to a more favourable outcome.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Osterloh J., Lotti M., Pond S. M. Toxicologic studies in a fatal overdose of 2,4-D, MCPP, and chlorpyrifos. J Anal Toxicol. 1983 May-Jun;7(3):125–129. doi: 10.1093/jat/7.3.125. [DOI] [PubMed] [Google Scholar]
- Prescott L. F., Park J., Darrien I. Treatment of severe 2,4-D and mecoprop intoxication with alkaline diuresis. Br J Clin Pharmacol. 1979 Jan;7(1):111–116. doi: 10.1111/j.1365-2125.1979.tb00906.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Smysl B., Smyslová O., Kosatík A. Akute tödliche Ioxynilvergiftung. Arch Toxicol. 1977 Jul 19;37(3):241–245. doi: 10.1007/BF00355494. [DOI] [PubMed] [Google Scholar]
- Tomarken J. L., Britt B. A. Malignant hyperthermia. Ann Emerg Med. 1987 Nov;16(11):1253–1265. doi: 10.1016/s0196-0644(87)80235-4. [DOI] [PubMed] [Google Scholar]
- Wells W. D., Wright N., Yeoman W. B. Clinical features and management of poisoning with 2,4-D and mecoprop. Clin Toxicol. 1981 Mar;18(3):273–276. doi: 10.3109/15563658108990036. [DOI] [PubMed] [Google Scholar]