Abstract
Two cases of primary hypothyroidism with hypopituitarism in elderly patients are reported. The elevated levels of thyroid stimulating hormone led to delay in the recognition of accompanying pituitary failure. Elderly patients should not be commenced on thyroxine replacement therapy until the possibility of hypopituitarism and cortisol deficiency has been excluded.
Full text
PDF

Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Belchetz P. E. Idiopathic hypopituitarism in the elderly. Br Med J (Clin Res Ed) 1985 Jul 27;291(6490):247–248. doi: 10.1136/bmj.291.6490.247. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Blandford R. L., Samanta A. K., Burden A. C., Rosenthal F. D. Muscle contractures associated with glucocorticoid deficiency. Br Med J (Clin Res Ed) 1985 Jul 13;291(6488):127–128. doi: 10.1136/bmj.291.6488.127. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Faglia G., Bitensky L., Pinchera A., Ferrari C., Paracchi A., Beck-Peccoz P., Ambrosi B., Spada A. Thyrotropin secretion in patients with central hypothyroidism: evidence for reduced biological activity of immunoreactive thyrotropin. J Clin Endocrinol Metab. 1979 Jun;48(6):989–998. doi: 10.1210/jcem-48-6-989. [DOI] [PubMed] [Google Scholar]
- GOUDIE R. B., PINKERTON P. H. Anterior hypophysitis and Hashimoto's disease in a young woman. J Pathol Bacteriol. 1962 Apr;83:584–585. [PubMed] [Google Scholar]
- Hume R., Roberts G. H. Hypophysitis and hypopituitarism: report of a case. Br Med J. 1967 May 27;2(5551):548–550. doi: 10.1136/bmj.2.5551.548. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Primary hypothyroidism and hypopituitarism in a young woman. Am J Med. 1984 Aug;77(2):319–330. doi: 10.1016/0002-9343(84)90710-1. [DOI] [PubMed] [Google Scholar]
- Qureshi K. N., Hodkinson H. M. Evaluation of a ten-question mental test in the institutionalized elderly. Age Ageing. 1974 Aug;3(3):152–157. doi: 10.1093/ageing/3.3.152. [DOI] [PubMed] [Google Scholar]