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. 1989 Sep;65(767):628–631. doi: 10.1136/pgmj.65.767.628

Psychiatric morbidity in primary hyperparathyroidism.

S J McAllion 1, C R Paterson 1
PMCID: PMC2429194  PMID: 2608590

Abstract

Psychiatric symptoms are well recognized as a feature of patients with primary hyperparathyroidism. We have applied a standardized psychiatric interview to 15 patients before and after surgery. Thirteen had a lower 'psychiatric score' (less psychiatric morbidity) after surgery and improvements were particularly seen in symptoms of fatigue, depression, irritability, sleep disturbance and lack of concentration. The levels of intellectual impairment and of anxiety were unchanged after surgery. The 'psychiatric scores' in an additional group of 21 hyperparathyroid patients, in whom a decision to treat conservatively had been made independently, were similar to those in the surgically treated patients after surgery. Among all the untreated patients no relationship was found between overall 'psychiatric score' and serum levels of calcium or parathyrin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adams P. H. Conservative management of primary hyperparathyroidism. J R Coll Physicians Lond. 1982 Jul;16(3):184–190. [PMC free article] [PubMed] [Google Scholar]
  2. Alarcón R. D., Franceschini J. A. Hyperparathyroidism and paranoid psychosis. Case report and review of the literature. Br J Psychiatry. 1984 Nov;145:477–486. doi: 10.1192/bjp.145.5.477. [DOI] [PubMed] [Google Scholar]
  3. Alveryd A., Boström H., Wengle B., Wester P. O. Indications for surgery in the elderly patient with primary hyperparathyroidism. Acta Chir Scand. 1976;142(7):491–494. [PubMed] [Google Scholar]
  4. COPE O. Hyperparathyroidism: diagnosis and management. Am J Surg. 1960 Apr;99:394–403. doi: 10.1016/0002-9610(60)90134-3. [DOI] [PubMed] [Google Scholar]
  5. Cowie A. G. Morbidity in adult parathyroid surgery. J R Soc Med. 1982 Dec;75(12):942–945. doi: 10.1177/014107688207501204. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Goldberg D. P., Cooper B., Eastwood M. R., Kedward H. B., Shepherd M. A standardized psychiatric interview for use in community surveys. Br J Prev Soc Med. 1970 Feb;24(1):18–23. doi: 10.1136/jech.24.1.18. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Gough M. H., Smith R., Bishop M. C. Parathyroidectomy for symptomless hyperparathyroidism: a surgical dilemma. Lancet. 1971 Jun 5;1(7710):1178–1178. doi: 10.1016/s0140-6736(71)91679-5. [DOI] [PubMed] [Google Scholar]
  8. Heath D. A., Wright A. D., Barnes A. D., Oates G. D., Dorricott N. J. Surgical treatment of primary hyperparathyroidism in the elderly. Br Med J. 1980 Jun 14;280(6229):1406–1408. doi: 10.1136/bmj.280.6229.1406. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Hecht A., Gershberg H., St Paul H. Primary hyperparathyroidism. Laboratory and clinical data in 73 cases. JAMA. 1975 Aug 11;233(6):519–526. doi: 10.1001/jama.233.6.519. [DOI] [PubMed] [Google Scholar]
  10. Joborn C., Hetta J., Frisk P., Palmér M., Akerström G., Ljunghall S. Primary hyperparathyroidism in patients with organic brain syndrome. Acta Med Scand. 1986;219(1):91–98. doi: 10.1111/j.0954-6820.1986.tb03281.x. [DOI] [PubMed] [Google Scholar]
  11. Joborn C., Hetta J., Johansson H., Rastad J., Agren H., Akerström G., Ljunghall S. Psychiatric morbidity in primary hyperparathyroidism. World J Surg. 1988 Aug;12(4):476–481. doi: 10.1007/BF01655425. [DOI] [PubMed] [Google Scholar]
  12. Paterson C. R., Burns J., Mowat E. Long term follow up of untreated primary hyperparathyroidism. Br Med J (Clin Res Ed) 1984 Nov 10;289(6454):1261–1263. doi: 10.1136/bmj.289.6454.1261. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Pattie A. H., Gilleard C. J. A brief psychogeriatric assessment schedule. Validation against psychiatric diagnosis and discharge from hospital. Br J Psychiatry. 1975 Nov;127:489–493. doi: 10.1192/bjp.127.5.489. [DOI] [PubMed] [Google Scholar]
  14. Posen S., Clifton-Bligh P., Reeve T. S., Wagstaffe C., Wilkinson M. Is parathyroidectomy of benefit in primary hyperparathyroidism? Q J Med. 1985 Mar;54(215):241–251. [PubMed] [Google Scholar]
  15. Scott H. W., Jr, Richie R. E., Crane J. M., Rosenfeld L., Jacobs J. K., Ginn E., Liddle G. W., Brannan A. N. Surgical experience with hyperparathyroidism. Am Surg. 1981 Feb;47(2):54–62. [PubMed] [Google Scholar]

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