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. 1990 Feb;66(772):132–133. doi: 10.1136/pgmj.66.772.132

Hyperthyroidism during pregnancy due to coexistence of struma ovarii and Graves' disease.

A W Kung 1, J T Ma 1, C Wang 1, R T Young 1
PMCID: PMC2429546  PMID: 2349185

Abstract

A patient with hyperthyroid Graves' disease and struma ovarii is described. She had pre-existing Graves' disease and positive thyrotrophin receptor antibody. She was treated with radioactive iodine 5 months before she became pregnant. Paripartum she had torsion of an ovarian cyst with histological evidence of a functional struma ovarii. Immediate exacerbation of her thyrotoxic state was observed after operation as a result of release of thyroid hormone from the tumour. It is postulated that the tumour was stimulated by circulating thyrotrophin receptor antibody.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bortolozzi G. Lo struma ovarico (prèsentazione di 5 casi e rassegna della letteratura) Ann Ostet Ginecol Med Perinat. 1967 May;89(5):310–331. [PubMed] [Google Scholar]
  2. Brown W. W., Shetty K. R., Rosenfeld P. S. Hyperthyroidism due to struma ovarii: demonstration by radioiodine scan. Acta Endocrinol (Copenh) 1973 Jun;73(2):266–272. doi: 10.1530/acta.0.0730266. [DOI] [PubMed] [Google Scholar]
  3. Hasleton P. S., Kelehan P., Whittaker J. S., Burslem R. W., Turner L. Benign and malignant struma ovarii. Arch Pathol Lab Med. 1978 Apr;102(4):180–184. [PubMed] [Google Scholar]
  4. Lefort G., Commenges-Ducos M., Denechaud M., Rivel J., Latapie J. L. Goitre ovarien au cours d'une maladie de Basedow. Rôle des immunoglobulines thyréostimulantes? Nouv Presse Med. 1981 Jun 13;10(26):2209–2210. [PubMed] [Google Scholar]
  5. MARCUS C. C., MARCUS S. L. Struma ovarii. A report of 7 cases and a review of the subject. Am J Obstet Gynecol. 1961 Apr;81:752–762. [PubMed] [Google Scholar]
  6. Smith B. R., Hall R. Thyroid-stimulating immunoglobulins in Graves' disease. Lancet. 1974 Aug 24;2(7878):427–431. doi: 10.1016/s0140-6736(74)91815-7. [DOI] [PubMed] [Google Scholar]
  7. Valente W. A., Vitti P., Rotella C. M., Vaughan M. M., Aloj S. M., Grollman E. F., Ambesi-Impiombato F. S., Kohn L. D. Antibodies that promote thyroid growth. A distinct population of thyroid-stimulating autoantibodies. N Engl J Med. 1983 Oct 27;309(17):1028–1034. doi: 10.1056/NEJM198310273091705. [DOI] [PubMed] [Google Scholar]
  8. Yeh E. L., Meade R. C., Ruetz P. P. Radionuclide study of struma ovarii. J Nucl Med. 1973 Feb;14(2):118–121. [PubMed] [Google Scholar]

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