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. 1990 Aug;66(778):664–666. doi: 10.1136/pgmj.66.778.664

Early diagnosis of Graves' optic neuropathy using visual evoked responses.

J A Batch 1, F Lepre 1
PMCID: PMC2429688  PMID: 2217037

Abstract

A 27 year old woman with Graves' disease developed progressive ophthalmopathy and was noted to have abnormal visual evoked responses (VER). She was treated with high dose prednisone with clinical improvement and return of the visual evoked responses to normal. On withdrawal of steroids symptoms recurred and VER again were abnormal. Orbital irradiation was given with improvement in the ophthalmopathy and VER again normalized. To our knowledge this report represents the first demonstration of improvement in VER with treatment in Graves' optic neuropathy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chiappa K. H., Ropper A. H. Evoked potentials in clinical medicine (first of two parts). N Engl J Med. 1982 May 13;306(19):1140–1150. doi: 10.1056/NEJM198205133061904. [DOI] [PubMed] [Google Scholar]
  2. Gasser P., Flammer J. Optic neuropathy of Graves' disease. A report of a perimetric follow-up. Ophthalmologica. 1986;192(1):22–27. doi: 10.1159/000309607. [DOI] [PubMed] [Google Scholar]
  3. HENDERSON J. W. Optic neuropathy of exophthalmic goiter (Graves' disease). AMA Arch Ophthalmol. 1958 Apr;59(4):471–480. doi: 10.1001/archopht.1958.00940050027001. [DOI] [PubMed] [Google Scholar]
  4. Maroon J. C., Kennerdell J. S. Radical orbital decompression for severe dysthyroid exophthalmos. J Neurosurg. 1982 Feb;56(2):260–266. doi: 10.3171/jns.1982.56.2.0260. [DOI] [PubMed] [Google Scholar]
  5. Olivotto I. A., Ludgate C. M., Allen L. H., Rootman J. Supervoltage radiotherapy for Graves' ophthalmopathy: CCABC technique and results. Int J Radiat Oncol Biol Phys. 1985 Dec;11(12):2085–2090. doi: 10.1016/0360-3016(85)90088-4. [DOI] [PubMed] [Google Scholar]
  6. Peyster R. G., Hoover E. D., Hershey B. L., Haskin M. E. High-resolution CT of lesions of the optic nerve. AJR Am J Roentgenol. 1983 May;140(5):869–874. doi: 10.2214/ajr.140.5.869. [DOI] [PubMed] [Google Scholar]
  7. Sergott R. C., Glaser J. S. Graves' ophthalmopathy. A clinical and immunologic review. Surv Ophthalmol. 1981 Jul-Aug;26(1):1–21. doi: 10.1016/0039-6257(81)90120-x. [DOI] [PubMed] [Google Scholar]
  8. Trobe J. D., Glaser J. S., Laflamme P. Dysthyroid optic neuropathy. Clinical profile and rationale for management. Arch Ophthalmol. 1978 Jul;96(7):1199–1209. doi: 10.1001/archopht.1978.03910060033007. [DOI] [PubMed] [Google Scholar]
  9. Trobe J. D. Optic nerve involvement in dysthyroidism. Ophthalmology. 1981 Jun;88(6):488–492. doi: 10.1016/s0161-6420(81)34997-5. [DOI] [PubMed] [Google Scholar]
  10. Weetman A. P., McGregor A. M., Ludgate M., Beck L., Mills P. V., Lazarus J. H., Hall R. Cyclosporin improves Graves' ophthalmopathy. Lancet. 1983 Aug 27;2(8348):486–489. doi: 10.1016/s0140-6736(83)90514-7. [DOI] [PubMed] [Google Scholar]
  11. Wijngaarde R., van Lith G. H. Pattern EPS in endocrine orbitopathy. Doc Ophthalmol. 1980 Apr 15;48(2):327–332. doi: 10.1007/BF00141461. [DOI] [PubMed] [Google Scholar]

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