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. Author manuscript; available in PMC: 2009 May 2.
Published in final edited form as: Vaccine. 2008 Mar 31;26(19):2335–2343. doi: 10.1016/j.vaccine.2008.02.064

Figure 5. Immunization of dogs with rH_EIV provides partial clinical protection against challenge with virulent CIV.

Figure 5

Two groups of four dogs were vaccinated s.c. twice with rH_EIV or mock-vaccinated. All dogs were challenged 3 weeks after booster vaccination with 1×106 PFU A/canine/PA/10915-07 and physical exams were performed on days 0–8, 10, and 15. The clinical score given to each individual was based on several clinical signs, as described under Mat. & Meth (A). Body temperatures were also measured in these dogs and fever was defined as a rectal temperature of ≥ 39.4°C (B). Asterisks indicate statistically significant differences.