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. 1997 Mar;73(857):146–150. doi: 10.1136/pgmj.73.857.146

The role of cell migration and microchimerism in the induction of tolerance after solid organ transplantation.

R M Jindal 1, A Sahota 1
PMCID: PMC2431236  PMID: 9135829

Abstract

A new hypothesis has been proposed which states that microchimerism is the basis for the clinical tolerance seen in long-term survivors of solid organ transplants. Efforts to enhance microchimerism include simultaneous infusion of bone marrow of donor origin and transplantation of a solid organ. Studies are in progress to verify the phenomenon of microchimerism and its role in clinical tolerance.

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Selected References

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