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. 1978 Nov;36(5):700–704. doi: 10.1128/aem.36.5.700-704.1978

Surface kinetic test method for determining rate of kill by an antimicrobial solid.

A J Isquith, C J McCollum
PMCID: PMC243124  PMID: 365109

Abstract

An antimicrobial-surface kinetic test which maximizes probability of cell-to-surface contact has been developed. The measurement of rate of kill by a nonleaching antimicrobial surface is based on the number of surviving bacterial cells at specific times of exposure to various amounts of total treated surface area of test substrate. This method gives information for direct comparison of rate of kill for a variety of antimicrobial surfaces in terms of rate of kill per square centimeter of surface area. Data obtained by this method can also give valuable dose response application information as an indication of the exponential efficiency of concentration in terms of treated surface area.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DUNKLIN E. W., LESTER W., Jr Residual surface disinfection. II. The effect of orthophenylphenol treatment of the floor on bacterial contamination in a recovery room. J Infect Dis. 1959 Jan-Feb;104(1):41–55. doi: 10.1093/infdis/104.1.41. [DOI] [PubMed] [Google Scholar]
  2. Isquith A. J., Abbott E. A., Walters P. A. Surface-bonded antimicrobial activity of an organosilicon quaternary ammonium chloride. Appl Microbiol. 1972 Dec;24(6):859–863. doi: 10.1128/am.24.6.859-863.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. KLARMAN E. G., WRIGHT E. S., SHTER V. A. Prolongation of the antibacterial potential of disinfected surfaces. Appl Microbiol. 1953 Jan;1(1):19–23. doi: 10.1128/am.1.1.19-23.1953. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. LESTER W., Jr, DUNKLIN E. W. Residual surface disinfection. I. The prolonged germicidal action of dried surfaces treated with orthophenylphenol. J Infect Dis. 1955 Jan-Feb;96(1):40–53. doi: 10.1093/infdis/96.1.40. [DOI] [PubMed] [Google Scholar]
  5. Walters P. A., Abbott E. A., Isquith A. J. Algicidal activity of a surface-bonded organosilicon quaternary ammonium chloride. Appl Microbiol. 1973 Feb;25(2):253–256. doi: 10.1128/am.25.2.253-256.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Won C. M., Garrett E. R. Kinetics and mechanisms of action of drugs on microorganisms. XVI. Effect of oleandomycin and its combinations with tetracycline, chloramphenicol, erythromycin, lincomycin, and 1'-demethyl-4'-depropyl-4'-(R and S)-n-pentylclindamycin on microbial generation of Escherichia coli. J Pharm Sci. 1973 Jul;62(7):1087–1092. doi: 10.1002/jps.2600620707. [DOI] [PubMed] [Google Scholar]

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