Abstract
We present a 78-year-old woman with clinical acute hypopituitarism in whom pathologic findings showed lymphocytic hypophysitis and retroperitoneal fibrosis. Lymphocytic hypophysitis should be included in the differential diagnosis of hypopituitarism at any age. The association with idiopathic retroperitoneal fibrosis suggest an autoimmune origin for this entity.
Full text
PDF


Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Burke C. W., Moore R. A., Rees L. H., Bottazzo G. F., Mashiter K., Bitensky L. Isolated ACTH deficiency and TSH deficiency in the adult. J R Soc Med. 1979 May;72(5):328–335. doi: 10.1177/014107687907200505. [DOI] [PMC free article] [PubMed] [Google Scholar]
- CARPENTER C. C., SOLOMON N., SILVERBERG S. G., BLEDSOE T., NORTHCUTT R. C., KLINENBERG J. R., BENNETT I. L., Jr, HARVEY A. M. SCHMIDT'S SYNDROME (THYROID AND ADRENAL INSUFFICIENCY). A REVIEW OF THE LITERATURE AND A REPORT OF FIFTEEN NEW CASES INCLUDING TEN INSTANCES OF COEXISTENT DIABETES MELLITUS. Medicine (Baltimore) 1964 Mar;43:153–180. [PubMed] [Google Scholar]
- Cosman F., Post K. D., Holub D. A., Wardlaw S. L. Lymphocytic hypophysitis. Report of 3 new cases and review of the literature. Medicine (Baltimore) 1989 Jul;68(4):240–256. doi: 10.1097/00005792-198907000-00006. [DOI] [PubMed] [Google Scholar]
- Komatsu M., Kondo T., Yamauchi K., Yokokawa N., Ichikawa K., Ishihara M., Aizawa T., Yamada T., Imai Y., Tanaka K. Antipituitary antibodies in patients with the primary empty sella syndrome. J Clin Endocrinol Metab. 1988 Oct;67(4):633–638. doi: 10.1210/jcem-67-4-633. [DOI] [PubMed] [Google Scholar]
- Levine S. Allergic adenohypophysitis: new experimental disease of the pituitary gland. Science. 1967 Dec 1;158(3805):1190–1191. doi: 10.1126/science.158.3805.1190. [DOI] [PubMed] [Google Scholar]
- Paja M., Estrada J., Ojeda A., Ramón y Cajal S., García-Uría J., Lucas T. Lymphocytic hypophysitis causing hypopituitarism and diabetes insipidus, and associated with autoimmune thyroiditis, in a non-pregnant woman. Postgrad Med J. 1994 Mar;70(821):220–224. doi: 10.1136/pgmj.70.821.220. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sobrinho-Simões M., Brandão A., Paiva M. E., Vilela B., Fernandes E., Carneiro-Chaves F. Lymphoid hypophysitis in a patient with lymphoid thyroiditis, lymphoid adrenalitis, and idiopathic retroperitoneal fibrosis. Arch Pathol Lab Med. 1985 Mar;109(3):230–233. [PubMed] [Google Scholar]
- Stacpoole P. W., Interlandi J. W., Nicholson W. E., Rabin D. Isolated ACTH deficiency: a heterogeneous disorder. Critical review and report of four new cases. Medicine (Baltimore) 1982 Jan;61(1):13–24. [PubMed] [Google Scholar]
- Vance M. L. Hypopituitarism. N Engl J Med. 1994 Jun 9;330(23):1651–1662. doi: 10.1056/NEJM199406093302306. [DOI] [PubMed] [Google Scholar]


