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. 1979 Nov;38(5):934–939. doi: 10.1128/aem.38.5.934-939.1979

Evaluation of a class III biological safety cabinet for enclosure of an ultracentrifuge.

M A Chatigny, S Dunn, K Ishimaru, J A Eagleson, S B Prusiner
PMCID: PMC243612  PMID: 543704

Abstract

An evaluation of a special safety cabinet housing a high-speed centrifuge was made. The cabinet enclosed both the top access port and the drive and pumping machinery of the centrifuge. A titanium rotor was loaded with tubes containing a bacterial culture, weakened, and driven until rotor rupture occurred. There were several bent and broken components in the centrifuge, and bacteria leaked from the vacuum chamber. Although the forces were sufficient to displace the cabinet, none of the test bacteria were found outside the cabinet.

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Selected References

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  1. Stern E. L., Johnson J. W., Vesley D., Halbert M. M., Lawrence B. S., Williams L. E., Blume P. Aerosol production associated with clinical laboratory procedures. Am J Clin Pathol. 1974 Nov;62(5):591–600. doi: 10.1093/ajcp/62.5.591. [DOI] [PubMed] [Google Scholar]

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